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020 _a9781071644744
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024 7 _a10.1007/978-1-0716-4474-4
_2doi
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082 0 4 _a612.8
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245 1 0 _aBlood-Brain Barrier
_h[electronic resource] /
_cedited by Tatiana Barichello.
250 _a2nd ed. 2025.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2025.
300 _aXIV, 392 p. 83 illus., 73 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
341 0 _bTable of contents navigation
_2onix
341 0 _bSingle logical reading order
_2onix
341 0 _bShort alternative textual descriptions
_2onix
341 0 _bUse of color is not sole means of conveying information
_2onix
341 0 _bUse of high contrast between text and background color
_2onix
341 0 _bNext / Previous structural navigation
_2onix
341 0 _bAll non-decorative content supports reading without sight
_2onix
347 _atext file
_bPDF
_2rda
490 1 _aNeuromethods,
_x1940-6045 ;
_v221
505 0 _aAn Overview of the Blood-Brain Barrier -- Differentiation of brain mural cells from human pluripotent stem cell-derived neural crest by activation of Notch3 signaling -- In vitro 2D and 3D cell models of the human blood-brain barrier: demonstrating the beneficial influence of shear stress on brain microvascular endothelial cell phenotype -- Emerging human choroid plexus organoid models for blood–CSF barrier research -- Drosophila as a model to study the blood-brain barrier. -Exploring the use of zebrafish in the blood-brain barrier research -- Evaluation and quantification of blood-brain barrier permeability in a photothrombotic juvenile rodent stroke model using in-vivo MRI and histology -- Transepithelial/transendothelial electrical resistance (TEER) to measure the integrity of blood-brain barrier -- Cell penetrating peptide-decorated nanovectors for nose-to-brain delivery - a new treatment option for CNS diseases -- Microbial Translocation of the Blood-Brain Barrier -- Microdialysis sampling in a free-moving mouse for blood-brain barrier studies -- Methods of Delivering Molecules Through the Blood-Brain Barrier for Brain Diagnostics and Therapeutics -- Transport across the choroid plexus: How to culture choroid plexus epithelial cells and establish a functional assay system -- Increasing BBB Permeability via Focused Ultrasound and Microbubbles: Current Methods in Pre-Clinical Research -- Recording leukocyte rolling and adhesion on meningeal vessels by intravital microscopy -- Molecular Imaging of Blood-Brain Barrier Permeability in Preclinical Models Using PET and SPECT -- Biomarkers for Microvascular Proteins Detection: Blood-Brain Barrier Injury and Damage Measurement (IH, IF, EM, and Quantification of Tight Junction Integrity) -- Deep learning and machine learning algorithms: A Blood Brain Barrier Permeability Prediction Model with Accuracy.
520 _aThis volume details experimental research with applicable models to study physiology, biochemistry, and molecular biology of the blood-brain barrier (BBB). Chapters guide readers through the physiology of BBB, in vitro cell models to study the BBB, in vivo and ex vivo models to evaluate BBB, permeability, influx, efflux transportation, drug delivery through the BBB, invasive and non-invasive imaging techniques to study BBB; and molecular biomarkers. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and cutting-edge, Blood-Brain Barrier aims to ensure successful results in the further study of this vital field.
532 8 _aAccessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com.
532 8 _aNo reading system accessibility options actively disabled
532 8 _aPublisher contact for further accessibility information: accessibilitysupport@springernature.com
650 0 _aNeurosciences.
650 1 4 _aNeuroscience.
700 1 _aBarichello, Tatiana.
_eeditor.
_0(orcid)0000-0001-7776-8454
_1https://orcid.org/0000-0001-7776-8454
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071644737
776 0 8 _iPrinted edition:
_z9781071644751
776 0 8 _iPrinted edition:
_z9781071644768
830 0 _aNeuromethods,
_x1940-6045 ;
_v221
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-4474-4
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