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020 _a9781071634615
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024 7 _a10.1007/978-1-0716-3461-5
_2doi
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072 7 _aTEC059000
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082 0 4 _a610.28
_223
245 1 0 _aReverse Engineering of Regulatory Networks
_h[electronic resource] /
_cedited by Sudip Mandal.
250 _a1st ed. 2024.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2024.
300 _aX, 327 p. 72 illus., 64 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
341 0 _bTable of contents navigation
_2onix
341 0 _bSingle logical reading order
_2onix
341 0 _bShort alternative textual descriptions
_2onix
341 0 _bUse of color is not sole means of conveying information
_2onix
341 0 _bUse of high contrast between text and background color
_2onix
341 0 _bNext / Previous structural navigation
_2onix
341 0 _bAll non-decorative content supports reading without sight
_2onix
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2719
505 0 _aMolecular Modeling Techniques and in-Silico Drug Discovery -- Systems Biology Approach to Analyse Microarray Datasets for Identification of Disease-Causing Genes: Case Study of Oral Squamous cell Carcinoma -- Fluorescence Spectroscopy: A Useful Method to Explore the Interactions of Small Molecule Ligands with DNA Structures -- Inference of Dynamic Growth Regulatory Network in Cancer Using high-Throughput Transcriptomic Data -- Implementation of Exome Sequencing to Identify Rare Genetic Diseases -- Emerging Trends in Big Data Analysis in Computational Biology and Bioinformatics in Health Informatics: A Case Study on Epilepsy and Seizures -- New Insights into Clinical Management for Sickle-Cell Disease: Uncovering the Significance Pathways Affected By the Involvement of Sickle Cell Disease -- A Review on Computational Approach for S-system Based Modeling of Gene Regulatory Network -- Big Data in Bioinformatics and Computational Biology: Basic Insights -- Identification of Culprit Genes for Different Diseases by Analysing Microarray Data -- Big Data Analysis in Computational Biology and Bioinformatics -- Prediction and Analysis of Transcription Factor Binding Sites to Understand Gene Regulation: Practical Examples and Case Studies using R Programming -- Hubs and Bottlenecks in Protein-Protein Interaction Networks -- Next-Generation Sequencing to Study the DNA Interaction Nac Deep Learning for Predicting Gene Regulatory Networks: A Step-by-Step Protocol in R -- Deep Learning for Predicting Gene Regulatory Networks: A Step-by-Step Protocol in R -- Computational inference of Gene Regulatory Network using genome-wide ChIP-X data -- Reverse Engineering in Biotechnology: The Role of Genetic Engineering in Synthetic Biology.
520 _aThis volume details the development of updated dry lab and wet lab based methods for the reconstruction of Gene regulatory networks (GRN). Chapters guide readers through culprit genes, in-silico drug discovery techniques, genome-wide ChIP-X data, high-Throughput Transcriptomic Data Exome Sequencing, Next-Generation Sequencing, Fuorescence Spectroscopy, data analysis in Bioinformatics, Computational Biology, and S-system based modeling of GRN. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Reverse Engineering of Regulatory Networks aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. .
532 8 _aAccessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com.
532 8 _aNo reading system accessibility options actively disabled
532 8 _aPublisher contact for further accessibility information: accessibilitysupport@springernature.com
650 0 _aBiomedical engineering.
650 0 _aGenetics.
650 0 _aBioinformatics.
650 1 4 _aBiomedical Engineering and Bioengineering.
650 2 4 _aGenetics.
650 2 4 _aBioinformatics.
700 1 _aMandal, Sudip.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071634608
776 0 8 _iPrinted edition:
_z9781071634622
776 0 8 _iPrinted edition:
_z9781071634639
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2719
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-3461-5
912 _aZDB-2-PRO
999 _c8024
_d8024