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001 978-1-61779-873-3
003 DE-He213
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020 _a9781617798733
_9978-1-61779-873-3
024 7 _a10.1007/978-1-61779-873-3
_2doi
050 4 _aQH426-470
072 7 _aPSAK
_2bicssc
072 7 _aSCI029000
_2bisacsh
072 7 _aPSAK
_2thema
082 0 4 _a576.5
_223
245 1 0 _aPrenatal Gene Therapy
_h[electronic resource] :
_bConcepts, Methods, and Protocols /
_cedited by Charles Coutelle, Simon N. Waddington.
250 _a1st ed. 2012.
264 1 _aTotowa, NJ :
_bHumana Press :
_bImprint: Humana,
_c2012.
300 _aX, 392 p. 33 illus., 7 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v891
520 _aThe emerging field of prenatal gene therapy is founded on scientific and technical advances in fetal medicine, molecular biology and gene therapy. This preclinical research subject aims at applying gene therapy during pregnancy for the prevention of human diseases caused by early onset congenital or gestation related conditions.  In Prenatal Gene Therapy: Concepts, Methods and Protocols, expert researchers in the field detail many of the protocols which are now commonly used to study gene therapy, fetal medicine and medical ethics. These include detailed protocols for vector production, for breeding and husbandry of the animal models, for  the surgical procedures of gene delivery in large and small animals and for the methods of gene transfer analysis. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Thorough and intuitive, Prenatal Gene Therapy: Concepts, Methods and Protocols seeks to aid scientists in the further study of prenatal disease and gene therapy projects beyond the scope of fetal medicine.
650 0 _aGenetics.
650 0 _aMedical genetics.
650 1 4 _aGenetics and Genomics.
650 2 4 _aMedical Genetics.
650 2 4 _aClinical Genetics.
700 1 _aCoutelle, Charles.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWaddington, Simon N.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781617798726
776 0 8 _iPrinted edition:
_z9781617798740
776 0 8 _iPrinted edition:
_z9781493959112
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v891
856 4 0 _uhttps://doi.org/10.1007/978-1-61779-873-3
912 _aZDB-2-PRO
999 _c7820
_d7820