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020 _a9781493914623
_9978-1-4939-1462-3
024 7 _a10.1007/978-1-4939-1462-3
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aPSF
_2thema
082 0 4 _a571.6
_223
245 1 0 _aVascular Morphogenesis
_h[electronic resource] :
_bMethods and Protocols /
_cedited by Domenico Ribatti.
250 _a1st ed. 2015.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Humana,
_c2015.
300 _aXI, 272 p. 61 illus., 40 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v1214
505 0 _aThe Development of the Vascular System: An Historical Overview -- The Corneal Pocket Assay -- The Mouse Hindbrain: An In Vivo Model to Analyze Developmental Angiogenesis -- Three Dimensional In Vitro Assay of Endothelial Cell Invasion and Capillary Tube Morphogenesis -- Vascular Casting for the Study of Vascular Morphogenesis -- Cell-Based Computational Modeling of Vascular Morphogenesis Using Tissue Simulation Toolkit -- miRNAs Expression Profile in Zebrafish Developing Vessels -- Imaging of Cardiovascular Development in Mammalian Embryos Using Optical Coherence Tomography -- Live Confocal Microscopy of the Developing Mouse Embryonic Yolk Sac Vasculature -- Zebrafish Embryo Intersegmental Vessels: A Tool for Investigating Sprouting Angiogenesis -- Avian Area Vasculosa and CAM as Rapid In Vivo Pro- and Anti-Angiogenic Models -- Investigating In Vitro Angiogenesis by Computer-Assisted Image Analysis and Computational Simulation -- A Chimeric Embryoid Body Model to Study Vascular Morphogenesis -- Avians as a Model System of Vascular Development -- Microfluidic Model of Angiogenic Sprouting -- The Rat Aortic Ring Model of Angiogenesis -- The Co-Culture Organotypic Assay of Angiogenesis.
520 _aVascular Morphogenesis: Methods and Protocols provides a range of techniques for studying vascular morphogenesis in vivo and in vitro, reflecting advances in the field. Endothelial cell signaling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation, and postnatal tissue remodeling. Understanding the concept of vascular bed specificity represents a major challenge for future investigations. Indeed, one of the most interesting theoretical perspectives and practical applications of endothelial cell signaling is the possibility for these cells to maintain their inductive potential during adult life. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Vascular Morphogenesis: Methods and Protocols will serve as a instructive and useful reference for cell biologists, anatomists, pathologists, and physiologists, as well as all those interested in this area of biological study.
650 0 _aCytology.
650 0 _aBlood-vessels
_xDiseases.
650 1 4 _aCell Biology.
650 2 4 _aAngiology.
700 1 _aRibatti, Domenico.
_eeditor.
_0(orcid)0000-0003-4768-8431
_1https://orcid.org/0000-0003-4768-8431
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781493914616
776 0 8 _iPrinted edition:
_z9781493914630
776 0 8 _iPrinted edition:
_z9781493948109
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v1214
856 4 0 _uhttps://doi.org/10.1007/978-1-4939-1462-3
912 _aZDB-2-PRO
999 _c7788
_d7788