000 04378nam a22005055i 4500
001 978-1-59259-256-2
003 DE-He213
005 20260610083659.0
007 cr nn 008mamaa
008 100301s1998 xxu| s |||| 0|eng d
020 _a9781592592562
_9978-1-59259-256-2
024 7 _a10.1007/978-1-59259-256-2
_2doi
050 4 _aQD71-142
072 7 _aPNF
_2bicssc
072 7 _aSCI013010
_2bisacsh
072 7 _aPNF
_2thema
082 0 4 _a543
_223
245 1 0 _aNatural Products Isolation
_h[electronic resource] /
_cedited by Richard J. P. Cannell.
250 _a1st ed. 1998.
264 1 _aTotowa, NJ :
_bHumana Press :
_bImprint: Humana,
_c1998.
300 _a480 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Biotechnology,
_x1940-607X ;
_v4
505 0 _aHow to Approach the Isolation of a Natural Product -- Initial Extraction and Product Capture -- Supercritical Fluid Methods -- Isolation by Low-Pressure Column Chromatography -- Isolation by Ion-Exchange Methods -- Isolation by Preparative HPLC -- Isolation by Planar Chromatography -- Separation by High-Speed Countercurrent Chromatography -- Crystallization and Final Stages of Purification -- Dereplication and Partial Identification of Natural Products -- Purification of Water-Soluble Natural Products -- Special Problems with the Extraction of Plants -- Isolation of Marine Natural Products -- Scale-Up of Natural Products Isolation -- Follow-Up of Natural Product Isolation.
520 _aNatural Products Isolation provides a comprehensive introduction to techniques for the extraction and purification of natural products from all biological sources. The book opens with an introduction to separations and chromatography and discusses the approach to an isolation. Experienced experimentalists describe a wide array of methods for isolation of both known and unknown natural products, including initial extraction, open column chromatography, HPLC, countercurrent and planar chromatography, SFE, and crystallisation. Later chapters address specific issues in working with plants, marine organisms, water-soluble compounds, as well as scale-up, dereplication and follow-up of a natural product lead. For the less experienced, these chapters provide background information and hands-on advice - using real examples - about how to approach an extraction in general, when and how to apply a particular technique and how to modify conditions according to the nature of the compound being isolated. Geared to scientists with little experience of natural products extraction, but offering even skilled researchers valuable advice and insight, Natural Products Isolation lays the foundation for the potential extractor to isolate natural substances efficiently. Its methods and guidance will almost certainly play a major role in today's natural product discovery and development.
532 8 _aAccessibility summary: This PDF is not accessible. It is based on scanned pages and does not support features such as screen reader compatibility or descriptions for non-text content (e.g., images and graphs). However, it likely supports searchable and selectable text based on OCR (Optical Character Recognition). Users with accessibility needs may not be able to use this content effectively. Please contact us at through this accessibility request webform if you require assistance or an alternative format.
532 8 _aInaccessible, or known limited accessibility
532 8 _aNo reading system accessibility options actively disabled
532 8 _aPublisher contact for further accessibility information: accessibilitysupport@springernature.com
650 0 _aAnalytical chemistry.
650 1 4 _aAnalytical Chemistry.
700 1 _aCannell, Richard J. P.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9780896033627
776 0 8 _iPrinted edition:
_z9781489942661
776 0 8 _iPrinted edition:
_z9781489942678
830 0 _aMethods in Biotechnology,
_x1940-607X ;
_v4
856 4 0 _uhttps://doi.org/10.1007/978-1-59259-256-2
912 _aZDB-2-PRO
999 _c7175
_d7175