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020 _a9781493931361
_9978-1-4939-3136-1
024 7 _a10.1007/978-1-4939-3136-1
_2doi
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072 7 _aMFN
_2bicssc
072 7 _aMED107000
_2bisacsh
072 7 _aMFN
_2thema
082 0 4 _a616.042
_223
245 1 0 _aMicroarray Technology
_h[electronic resource] :
_bMethods and Applications /
_cedited by Paul C.H. Li, Abootaleb Sedighi, Lin Wang.
250 _a1st ed. 2016.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Humana,
_c2016.
300 _aXIV, 294 p. 79 illus., 54 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v1368
505 0 _aOverview of Microarray Technology -- Surface Functionalization for Immobilization of Probes on Microarrays -- The “clickable” Method for Oligonucleotide Immobilization onto Azide-Functionalized Microarrays -- Microarray Developed on Plastic Substrates -- Detection and Quantification of Micrornas By Ligase-Assisted Sandwich Hybridization on a Microarray -- Probe Design Strategies for Oligonucleotide Microarrays -- Analyzing Illumina Gene Expression Microarray Data Obtained from Human Whole Blood Cell and Blood Monocyte Samples -- Microarray Technology and its Applications for Detecting Plasma microRNA Biomarkers in Digestive Tract Cancers -- Application of DNA Microarray to Clinical Diagnostics -- High-throughput DNA Array for SNP Detection of KRAS Gene using a Centrifugal Microfluidic Device -- Single Nucleotide Polymorphisms as Genomic Markers for High-Throughput Pharmacogenomic Studies -- DNA Microarray-Based Diagnostics -- High-throughput Screening of Substrate Specificity for Protein Tyrosine Phosphatases (PTPs) On Phosphopeptide Microarrays -- Nanotechnology in the Fabrication of Protein Microarrays -- Epitope Mapping using Peptide Microarray in Autoantibody Profiling -- Preparation of Glycan Arrays using Pyridylaminated Glycans -- Competitive Immunoassays Using Antigen Microarrays -- Parallel Syntheses of Peptides on Teflon-patterned paper arrays (SyntArrays) -- Cell Microarrays for Biomedical Applications.
520 _aThis volume provides updates of this established field in both methods and applications, as well as advances in applications of the microarray method to biomarkers such as DNAs, RNAs, proteins, glycans and whole cells. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and practical, Microarray Technology: Methods and Applications aims to ensure successful results in the further study of this vital field.
650 0 _aMedical genetics.
650 0 _aBioinformatics.
650 1 4 _aMedical Genetics.
650 2 4 _aComputational and Systems Biology.
700 1 _aLi, Paul C.H.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSedighi, Abootaleb.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWang, Lin.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781493931354
776 0 8 _iPrinted edition:
_z9781493931378
776 0 8 _iPrinted edition:
_z9781493949076
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v1368
856 4 0 _uhttps://doi.org/10.1007/978-1-4939-3136-1
912 _aZDB-2-PRO
999 _c7030
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