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020 _a9781493974351
_9978-1-4939-7435-1
024 7 _a10.1007/978-1-4939-7435-1
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
072 7 _aMJCL
_2thema
082 0 4 _a571.978
_223
082 0 4 _a616.994
_223
245 1 0 _aMicroRNA and Cancer
_h[electronic resource] :
_bMethods and Protocols /
_cedited by Wei Wu.
250 _a2nd ed. 2018.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Humana,
_c2018.
300 _aXI, 222 p. 21 illus., 17 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v1699
505 0 _aNon- coding RNAs in DNA Damage Response: Opportunities for Cancer Therapeutics -- MicroRNAs in Breast Cancer: Diagnostic and Therapeutic Potential -- Involvement of miRNAs and Pseudogenes in Cancer -- microRNAs Reprogram Tumor Immune Response -- APOBEC Gene Expression Regulated by microRNAs -- MicroRNAs Changes the Landscape of Cancer Resistance -- MicroRNA, Noise, and Gene Expression Regulation -- Deep Sequencing Reveals a microRNA Expression Signature in Triple-negative Breast Cancer -- Detection of Plasma microRNA Signature in Osteosarcoma Patients -- Identification of E6/E7-dependent microRNAs in HPV-positive Cancer Cells -- Combination of Anti-miRNAs Oligonucleotides with Low Amounts of Chemotherapeutic Agents for Pancreatic Cancer Therapy -- Evaluation of microRNA Delivery in vivo -- Angiogenesis Analysis by in vitro Co-culture Assays in Transwell Chambers in Ovarian Cancer -- Application of Individual qPCR Performance Parameters for Quality Control of Circulating microRNA Data -- Construction of Multi-potent microRNA Sponge and its Functional Evaluation -- microRNA Sequencing Data Analysis Toolkits.
520 _aThis volume details basic principles of experimental and computational methods for the study of microRNAs in cancer research and, therefore, provides a firm grounding for those who wish to develop further applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, MicroRNA and Cancer: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.
650 0 _aCancer.
650 1 4 _aCancer Biology.
700 1 _aWu, Wei.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781493974337
776 0 8 _iPrinted edition:
_z9781493974344
776 0 8 _iPrinted edition:
_z9781493984855
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v1699
856 4 0 _uhttps://doi.org/10.1007/978-1-4939-7435-1
912 _aZDB-2-PRO
999 _c6567
_d6567