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020 _a9781071650196
_9978-1-0716-5019-6
024 7 _a10.1007/978-1-0716-5019-6
_2doi
050 4 _aRB131
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
072 7 _aMJCM
_2thema
082 0 4 _a616.0473
_223
082 0 4 _a571.96
_223
245 1 0 _aModels in Inflammation and Immunopharmacology
_h[electronic resource] /
_cedited by Lucas Secchim Ribeiro.
250 _a1st ed. 2026.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2026.
300 _aXIII, 284 p. 77 illus., 72 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2993
505 0 _aHandling and Experimentation with Germ-Free Mice -- Modeling Gut Barrier Dysfunction and Subsequent Opportunistic Infection by Candida albicans during Chemotherapy-Induced Intestinal Mucositis in Mice -- Direct Inoculation of Pathogenic Yeasts into Mouse Lung by Trans-Tracheal Instillation -- Murine Models of Experimental Periodontal Disease -- Infectious Models in Mice for Study of Gut Inflammation: Primary Cultures of Myenteric Neurons -- Intravital Microscopy of Mesenteric and Brain vessels: A Valuable Tool for Leukocyte Recruitment Evaluation -- Classical Histological Procedures with Murine Tissues -- Measurement of MPO, NAG, and EPO as an Indirect Quantification of Leukocyte Infiltration in Mouse Tissues -- Bridging Immunity and Hemostasis: Technical Foundations of Platelet-Leukocyte Co-Cultures -- Quantitative In Vitro and In Vivo Assays to Assess the Efferocytic Efficiency of Macrophages -- Physical Exercise as a Model for Investigation of the Inflammation Response in Mice -- Humanized Murine Model with Peripheral Blood Mononuclear Cells as a Strategy to Translate Experimental Biomedical Research -- Murine Models of Alphavirus Infection to Study the Immunopathogenesis of Pain -- Platforms to Evaluate Flavivirus-Induced Immunoinflammatory Responses and Their Pathogenesis -- Methods for Evaluating Neurotropic Viral Infections: Exploring Zika and Coronavirus Diseases -- In Vivo Preclinical Platforms to Study Coronavirus Infection.
520 _aThis volume provides readers with a detailed collection of in vitro and in vivo protocols developed to study inflammation and the interactions between host and micro-organisms. The chapters in this book cover a range of biological systems and methodological approaches such as direct inoculation of pathogenic yeasts into mouse lung by trans-tracheal instillation; murine models of experimental periodontal disease; quantitative in vitro and in vivo assays to assess the efferocytic efficiency of macrophages; murine models of alphavirus infection to study the immunopathogenesis of pain; and in vivo preclinical platforms to study coronavirus infection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Models in Inflammation and Immunopharmacology is a practical and conceptual resource for researchers studying inflammation and host-microorganism interactions. This book is also a valuable reference for educators, clinicians, and policymakers who want to understand the foundations of experimental design in biomedicine. .
532 8 _aAccessibility summary: This PDF was created before the adoption of current accessibility best practices. It includes searchable and selectable text but may not fully support features such as alternative descriptions for non-text content (e.g., images and charts) or complete screen reader compatibility. Users with accessibility requirements may encounter limitations. Please contact us at through this accessibility request webform if you require assistance or an alternative format.
532 8 _aNo reading system accessibility options actively disabled
532 8 _aPublisher contact for further accessibility information: accessibilitysupport@springernature.com
650 0 _aInflammation.
650 0 _aBiology
_xTechnique.
650 0 _aExperimental immunology.
650 0 _aPharmacology.
650 1 4 _aInflammation.
650 2 4 _aImmunological Techniques.
650 2 4 _aPharmacology.
700 1 _aSecchim Ribeiro, Lucas.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071650189
776 0 8 _iPrinted edition:
_z9781071650202
776 0 8 _iPrinted edition:
_z9781071650219
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2993
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-5019-6
912 _aZDB-2-PRO
999 _c6469
_d6469