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020 _a9781071613276
_9978-1-0716-1327-6
024 7 _a10.1007/978-1-0716-1327-6
_2doi
050 4 _aQH588.S83
072 7 _aPSC
_2bicssc
072 7 _aSCI072000
_2bisacsh
072 7 _aPSC
_2thema
082 0 4 _a571.6
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082 0 4 _a616.02774
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245 1 0 _aStem Cells and Good Manufacturing Practices
_h[electronic resource] :
_bMethods, Protocols, and Regulations /
_cedited by Kursad Turksen.
250 _a2nd ed. 2021.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2021.
300 _aXII, 288 p. 10 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2286
505 0 _aSwiss Fetal Transplantation Program and Non-Enzymatically Isolated Primary Progenitor Cell Types for Regenerative Medicine -- GMP Tiered Cell Banking of Non-Enzymatically Isolated Dermal Progenitor Fibroblasts for Allogenic Regenerative Medicine -- Progenitor Biological Bandages: An Authentic Swiss Tool for Safe Therapeutic Management of Burns, Ulcers, and Donor Site Grafts -- Validation of the Media Fill Method for Solid Tissue Processing in Good Manufacturing Practice-Compliant Cell Production -- The Isolation, Culturing, Cryopreservation, and the Preparation as a Final Cellular Product of the Umbilical Cord-Derived Mesenchymal Stem Cells Under Good Manufacturing Practices Conditions -- The Isolation, Culture, Cryopreservation, and the Preparation as a Final Cellular Product of the Skin-Derived Fibroblasts Under Good Manufacturing Practice Conditions -- The Isolation and Manufacture of GMP-Grade Bone Marrow Stromal Cells from Bone Specimens -- Scalable Manufacturing of Human Hematopoietic Stem/Progenitor Cells Exploiting a Co-Culture Platform with Mesenchymal Stromal Cells -- GMP-Compatible, Xeno-Free Culture of Human Induced Mesenchymal Stem Cells -- GMP-Grade Methods for Cardiac Progenitor Cells: Cell Bank Production and Quality Control -- Suspension Culture of Human Induced Pluripotent Stem Cells in Single-Use Vertical-WheelTM Bioreactors Using Aggregate and Microcarrier Culture Systems -- Addressing Manufacturing Challenges for Commercialization of iPSC-Based Therapies -- Standard Operating Procedure for the Good Manufacturing Practice-Compliant Production of Human Endometrial Stem Cells for Multiple Sclerosis -- GMP-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells -- GMP-Compliant Human Schwann Cells Manufacturing for Clinical Application -- GMP-Compliant Adenoviral Vectors for Gene Therapy -- Use of Multipotent Mesenchymal Stromal Cells, Fibrin, and Scaffolds in ihe Production of Clinical Grade Bone Tissue Engineering Products -- QualityManagement Systems (QMSs) of Human Tissue- and Cell-Based Product Manufacturing Facilities.
520 _aThis detailed book explores the utilization and delivery of stem cells for therapeutic purposes in patients in the clinic and the tightly controlled Good Manufacturing Practices (GMP) that make these powerful techniques possible. Fully updated and expanded from the first edition, this collection features a new set of protocols to arm stem cell biologists with protocols that are currently being used in a number of well-established facilities around the world. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up to date, Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations, Second Edition serves as an ideal guide for researchers aiming to drive continued improvementsto GMP and accelerate new stem cell treatments for patients in need.
650 0 _aStem cells.
650 0 _aChemistry, Technical.
650 1 4 _aStem Cell Biology.
650 2 4 _aIndustrial Chemistry.
700 1 _aTurksen, Kursad.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071613269
776 0 8 _iPrinted edition:
_z9781071613283
776 0 8 _iPrinted edition:
_z9781071613290
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2286
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-1327-6
912 _aZDB-2-PRO
999 _c5828
_d5828