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020 _a9781071602706
_9978-1-0716-0270-6
024 7 _a10.1007/978-1-0716-0270-6
_2doi
050 4 _aQH324.2-324.25
072 7 _aUY
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072 7 _aPS
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072 7 _aCOM082000
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072 7 _aPSAX
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082 0 4 _a570.285
_223
245 1 0 _aStructural Bioinformatics
_h[electronic resource] :
_bMethods and Protocols /
_cedited by Zoltán Gáspári.
250 _a1st ed. 2020.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2020.
300 _aXII, 256 p. 86 illus., 76 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2112
505 0 _aVisualization and Analysis of Protein Structures with LiteMol Suite -- Comparative Protein Structure Analysis with Bio3D-Web -- Using DALI for Protein Structure Comparison -- Assessing Protein Function through Structural Similarities with CATH -- Protein Thermal Stability Engineering using HoTMuSiC -- Contact Area-Based Structural Analysis of Proteins and their Complexes using CAD-Score -- A Comprehensive Computational Platform to Guide Drug Development using Graph-Based Signature Methods -- Systematic Exploration of Binding Modes of Ligands on Drug Targets -- Using MemBlob to Analyze Transmembrane Regions Based on Cryo-EM Maps -- Structural Characterization of Protein-Protein Interactions with pyDockSAXS -- Protein-Protein Modeling using Cryo-EM Restraints -- Modeling of Multimolecular Complexes -- Biological Assembly Comparison with VAST+ -- BioMagResBank (BMRB) as a Resource for Structural Biology -- Integrating MolecularSimulation and Experimental Data: A Bayesian/Maximum Entropy Reweighting Approach -- Evaluation and Selection of Dynamic Protein Structural Ensembles with CoNSEnsX+.
520 _aThis volume looks at the latest techniques used to perform comparative structure analyses, and predict and evaluate protein-ligand interactions. The chapters in this book cover tools and servers such as LiteMol; Bio3D-Web; DALI; CATH; HoTMuSiC, a contact-base protein structure analysis tool known as CAD-Score; PyDockSaxs and HADDOCK; CombDock and DockStar; the BioMagResBank database; as well as BME and CoNSEnsX+. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Structural Bioinformatics: Methods and Protocols is a practical guide for researchers to learn more about the aforementioned tools to further enhance their studies in the growing field of structural bioinformatics. Chapter 13 is open access under a CC-BY 4.0 license via link.springer.com.
650 0 _aBioinformatics.
650 1 4 _aBioinformatics.
700 1 _aGáspári, Zoltán.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071602690
776 0 8 _iPrinted edition:
_z9781071602713
776 0 8 _iPrinted edition:
_z9781071602720
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2112
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-0270-6
912 _aZDB-2-PRO
999 _c5716
_d5716