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020 _a9781071600269
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024 7 _a10.1007/978-1-0716-0026-9
_2doi
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072 7 _aCOM082000
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082 0 4 _a570.285
_223
245 1 0 _aeQTL Analysis
_h[electronic resource] :
_bMethods and Protocols /
_cedited by Xinghua Mindy Shi.
250 _a1st ed. 2020.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2020.
300 _aX, 252 p. 145 illus., 65 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2082
505 0 _aIntroductory Methods for eQTL Analyses -- Performing QTL and eQTL Analyses with the R-package GenomicTools -- eQTL Mapping using Transcription Factor Affinity -- Identification and Quantification of Splicing Quantitative Trait Loci -- Genome-wide Composite Interval Mapping (GCIM) of Expressional Quantitative Trait Loci in Backcross Population -- Combining eQTL and SNP Annotation Data to Identify Functional Noncoding SNPs in GWAS Trait-associated Regions -- Statistical and Machine Learning Methods for eQTL Analysis -- Sparse Regression Models for Unraveling Group and Individual Associations in eQTL Mapping -- Exploring Bayesian Approaches to eQTL Mapping through Probabilistic Programming -- High-order Association Mapping for Expression Quantitative Trait Loci -- Integration of Multi-omics Data for Expression Quantitative Trait Loci (eQTL) Analysis and eQTL Epistasis -- Sparse Partial Least Squares Methods for Joint Modular Pattern Discovery -- Expression Quantitative Trait Loci (eQTL) Analysis in Cancer -- QTL Analysis Beyond eQTLs -- Quantitative Trait Loci (QTL) Mapping -- Expression Quantitative Trait Loci Analysis in Multiple Tissues -- Tissue Specific eQTL in Zebrafish. .
520 _aThis volume details state-of-art eQTL analysis, where interdisciplinary researchers are provided both theoretical and practical guidance to eQTL analysis and interpretation. Chapters guide readers through methods and tools for eQTL and QTL analysis and the usage of such analysis in various scenarios. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, eQTL Analysis: Methods and Protocols to ensure successful results in the further study of this vital field. .
650 0 _aBioinformatics.
650 0 _aGenetics.
650 1 4 _aBioinformatics.
650 2 4 _aGenetics and Genomics.
700 1 _aShi, Xinghua Mindy.
_eeditor.
_0(orcid)0000-0003-4662-3177
_1https://orcid.org/0000-0003-4662-3177
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071600252
776 0 8 _iPrinted edition:
_z9781071600276
776 0 8 _iPrinted edition:
_z9781071600283
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2082
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-0026-9
912 _aZDB-2-PRO
999 _c5713
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