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020 _a9781071617120
_9978-1-0716-1712-0
024 7 _a10.1007/978-1-0716-1712-0
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aSCI089000
_2bisacsh
072 7 _aPSAN
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082 0 4 _a612.8
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245 1 0 _aNeurodegenerative Diseases Biomarkers
_h[electronic resource] :
_bTowards Translating Research to Clinical Practice /
_cedited by Philip V. Peplow, Bridget Martinez, Thomas A. Gennarelli.
250 _a1st ed. 2022.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2022.
300 _aXVIII, 565 p. 48 illus., 42 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aNeuromethods,
_x1940-6045 ;
_v173
505 0 _aPrevalence, Needs, Strategies, and Risk Factors for Neurodegenerative Diseases. Activation of Microglia and Macrophages in Neurodegenerative Diseases -- Activation of Astrocytes in Neurodegenerative Diseases -- Tau Pathology in Neurodegenerative Diseases -- Role of SIRT3 and Mitochondrial Dysfunction in Neurodegeneration -- Oxidative Stress and Cellular Dysfunction in Neurodegeneratiove Disease -- Biomarkers in Parkinson’s Disease -- Metabolomic Biomarkers in Parkinson’s Disease -- Neuroinflammation in Huntington’s Disease -- Biomarkers in Huntington Disease -- Biofluid Biomarkers of Amyotrophic Lateral Sclerosis -- MicroRNAs in Blood Serum, Blood Plasma, and Cerebrospinal Fluid as Diagnostic Biomarkers of Alzheimer’s Disease -- Tau Biomarkers for Long-Term Effects of Neurotrauma: Technology Versus the Null Hypothesis -- Impedimetric Immunosensing for Neuroinflammatory Biomarker Profiling -- Aptamers Detection of Neurodegenerative Disease Biomarkers -- Possible Biomarkers for Frontotemporal Dementia and to Differentiate from Alzheimer’s Disease and Amyotrophic Lateral Sclerosis -- TSPO PET Imaging as a Biomarker of Neuroinflammation in Neurodegenerative Disorders -- Validation of Diffusion Kurtosis Imaging as an Early Stage Biomarker of Parkinson’s Disease in Animal Models -- Imaging Biomarkers in Huntington’s Disease -- Imaging Biomarkers in Amyotrophic Lateral Sclerosis -- Trends in Biomarkers of Neurodegenerative Diseases.
520 _aThis volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in neurodegenerative diseases; TSPO PET imaging as a biomarker of neuroinflammation in neurodegenerative disorders; and imaging biomarkers in Huntington's disease and amyotrophic lateral sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice is a valuable resource for both experimental and clinical experts in the field of neurodegenerative diseases who are looking to expand their knowledge of novel biomarkers in different types of neurodegenerative diseases.
650 0 _aNeurosciences.
650 1 4 _aNeuroscience.
700 1 _aPeplow, Philip V.
_eeditor.
_0(orcid)0000-0001-5468-1989
_1https://orcid.org/0000-0001-5468-1989
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMartinez, Bridget.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aGennarelli, Thomas A.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071617113
776 0 8 _iPrinted edition:
_z9781071617137
776 0 8 _iPrinted edition:
_z9781071617144
830 0 _aNeuromethods,
_x1940-6045 ;
_v173
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-1712-0
912 _aZDB-2-PRO
999 _c5621
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