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020 _a9781071612330
_9978-1-0716-1233-0
024 7 _a10.1007/978-1-0716-1233-0
_2doi
050 4 _aRM300-666
072 7 _aMMG
_2bicssc
072 7 _aMED071000
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072 7 _aMKG
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082 0 4 _a615
_223
100 1 _aArunachalam, Karuppusamy.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aBioassays in Experimental and Preclinical Pharmacology
_h[electronic resource] /
_cby Karuppusamy Arunachalam, Sreeja Puthanpura Sasidharan.
250 _a1st ed. 2021.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2021.
300 _aXII, 271 p. 4 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Protocols Handbooks,
_x1949-2456
505 0 _aOverview -- Cell Culture Assays -- Phytochemical Analysis -- Preclinical Drug Dose Calculation -- Toxicology Studies (In Vitro and In Vivo) -- Standard Procedure for Anesthesia in Preclinical Experiments -- General Considerations and Collection of Animal Blood -- Animal Experiments on the Cardiovascular System -- Animal Experiments on Ulcerative Colitis -- Experiments on Anti-Bacterial Activities -- Experiments on Anti-Fungal Activities -- Animal Experiment on Wound Healing Activity -- Animal Experiments of Anti-inflammatory Activities -- Animal Experiment on Anti-Nociceptive Activities -- Experiments on Anti-Oxidant Activities -- Animal Experiments on Hepatoprotective Activities -- Animal Experiments on Anti-Diarrheal Activities -- Animal Experiments on Central Nervous System (CNS) -- Experiments on Anti-Cancer Activities (In Vitro and In Vivo) -- Animal Experiments on Anti-Diabetic Activities -- Animal Experiments on Gastric Ulcer -- Protein Extraction and Western Blot Analysis -- Gel Electrophoresis and PCR Amplification -- Molecular Docking Methods for Drug Design.
520 _aThis detailed book explores protocols for a wide array of preclinical pharmacology and toxicology evaluations to be applied to chemical drugs and their development through in vitro, involving tissues and cell lines, and in vivo models, using animals as experimental systems, utilized to conduct pharmacological research. Written for the Springer Protocols Handbooks series, the methodologies included in this collection have been standardized by the authors through extensive use in the lab so that they are ready to be applied in the labs of readers around the world. Authoritative and practical, Bioassays in Experimental and Preclinical Pharmacology aims to assist undergraduate and postgraduate students, research scholars, scientists, and other academicians performing research in the vital field of drug discovery.
650 0 _aPharmacology.
650 0 _aMedical sciences.
650 0 _aDrug development.
650 0 _aToxicology.
650 0 _aPharmacovigilance.
650 1 4 _aPharmacology.
650 2 4 _aPreclinical Research.
650 2 4 _aToxicology.
650 2 4 _aDrug Safety and Pharmacovigilance.
700 1 _aSasidharan, Sreeja Puthanpura.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071612323
776 0 8 _iPrinted edition:
_z9781071612347
776 0 8 _iPrinted edition:
_z9781071612354
830 0 _aSpringer Protocols Handbooks,
_x1949-2456
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-1233-0
912 _aZDB-2-PRO
999 _c5602
_d5602