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| 001 | 978-1-0716-2807-2 | ||
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| 008 | 221212s2023 xxu| s |||| 0|eng d | ||
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_a10.1007/978-1-0716-2807-2 _2doi |
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_aType-1 Diabetes _h[electronic resource] : _bMethods and Protocols / _cedited by Anna Moore, Ping Wang. |
| 250 | _a1st ed. 2023. | ||
| 264 | 1 |
_aNew York, NY : _bSpringer US : _bImprint: Humana, _c2023. |
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| 300 |
_aXII, 252 p. 54 illus., 49 illus. in color. _bonline resource. |
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_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
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_aonline resource _bcr _2rdacarrier |
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_bTable of contents navigation _2onix |
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_bSingle logical reading order _2onix |
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_bShort alternative textual descriptions _2onix |
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_bUse of color is not sole means of conveying information _2onix |
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_bUse of high contrast between text and background color _2onix |
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_atext file _bPDF _2rda |
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_aMethods in Molecular Biology, _x1940-6029 ; _v2592 |
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| 505 | 0 | _a3D optical molecular imaging of the rodent pancreas by OPT and LSFM -- Uncommon Transplantation Sites – Transplantation of islets and islet organoids in the anterior chamber of the eye of rodents and monkeys -- Generation of Insulin-producing multicellular organoids -- Non-invasive quantitative PET Imaging in humans of the Pancreatic Beta Cell Mass biomarkers VMAT2 and Dopamine, D2/D3 receptors, in vivo -- In Vivo Imaging of Naked and Microencapsulated Islet Cell Transplantation -- Diabetes retinopathy: new ways to detect and treat -- MRI methods for imaging beta-cell function in the rodent pancreas -- MicroRNAs in type 2 diabetes – focus on microRNA profiling in Islets of Langerhans -- Protocol for clinical GLP-1 receptor PET/CT imaging with [68Ga]Ga-NODAGA-exendin-4 -- Hyperinsulinemic-euglycemic clamp in conscious rats based on the tail artery and vein catheterization -- Synthesis of siRNA-conjugated dextran-coated iron oxide nanoparticles for islet protection during transplantation and noninvasive imaging -- Micelle-Based Nanocarriers for Targeted Delivery of Cargo to Pancreas -- Magnetic particle imaging of transplanted human islets using a machine learning algorithm -- In vivo bioluminescence for the detection of the fate of pancreatic islet organoids post-transplantation -- miRNA theranostic nanoparticles promote pancreatic beta cell proliferation in type 1 diabetes model -- Isolation and purification of human pancreatic islets -- Vascularized islet transplantation as composite Islet-Kidney grafts with nanoparticle-labeled islets in large animal preclinical transplant models. . | |
| 520 | _aThis volumes details methods focusing on technological innovation and recent advances in diabetes management. Chapters will guide readers through recent advances, beta-cell regeneration, non-invasive imaging of endogenous, transplanted islets theranostics, microRNA profiling of beta-cells and artificial intelligence, and deep learning algorithms in diabetes. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Type-1 Diabetes: Methods and Protocols is for a broad audience including basic researches, clinicians, and physician scientists whose major focus is in diabetes. | ||
| 532 | 8 | _aAccessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. | |
| 532 | 8 | _aNo reading system accessibility options actively disabled | |
| 532 | 8 | _aPublisher contact for further accessibility information: accessibilitysupport@springernature.com | |
| 650 | 0 |
_aMedicine _xResearch. |
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| 650 | 0 |
_aBiology _xResearch. |
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| 650 | 0 | _aEndocrinology. | |
| 650 | 1 | 4 | _aBiomedical Research. |
| 650 | 2 | 4 | _aEndocrinology. |
| 700 | 1 |
_aMoore, Anna. _eeditor. _0(orcid)0000-0002-5218-7204 _1https://orcid.org/0000-0002-5218-7204 _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 700 | 1 |
_aWang, Ping. _eeditor. _0(orcid)0000-0001-6712-8939 _1https://orcid.org/0000-0001-6712-8939 _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer Nature eBook | |
| 776 | 0 | 8 |
_iPrinted edition: _z9781071628065 |
| 776 | 0 | 8 |
_iPrinted edition: _z9781071628089 |
| 776 | 0 | 8 |
_iPrinted edition: _z9781071628096 |
| 830 | 0 |
_aMethods in Molecular Biology, _x1940-6029 ; _v2592 |
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| 856 | 4 | 0 | _uhttps://doi.org/10.1007/978-1-0716-2807-2 |
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