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020 _a9781071608227
_9978-1-0716-0822-7
024 7 _a10.1007/978-1-0716-0822-7
_2doi
050 4 _aQH324.2-324.25
072 7 _aUY
_2bicssc
072 7 _aPS
_2bicssc
072 7 _aCOM082000
_2bisacsh
072 7 _aPSAX
_2thema
082 0 4 _a570.285
_223
245 1 0 _aComputational Methods in Synthetic Biology
_h[electronic resource] /
_cedited by Mario Andrea Marchisio.
250 _a2nd ed. 2021.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2021.
300 _aX, 255 p. 97 illus., 58 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2189
505 0 _a1. Using a Design of Experiments Approach to Inform the Design of Hybrid Synthetic Yeast Promoters -- Computational Design of Multiplex Oligonucleotide-Based Assays -- Computational Methods For The Design Of Recombinase Logic Circuits -- Modular Modeling Of Genetic Circuits in SBML Level 3.-- CRISPR-ERA: A Webserver for Guide RNA Design of Gene Editing and Regulation -- iGUIDE Method for CRISPR Off-target Detection -- Web-based Base Editing Toolkits: BE-Designer and BE-Analyzer -- Synthetic Gene Circuit Analysis and Optimization -- Monitoring Single S. cerevisiae Cells with Multi-Frequency Electrical Impedance Spectroscopy in an Electrode-integrated Microfluidic Device -- Construction of Protein Expression Network -- Systems-theoretic Approaches to Design Biological Networks with Desired Functionalities -- A Deterministic Compartmental Modeling Framework for Disease Transmission -- Computer Aided Assembly and Verificationof Synthetic Chromosomes -- Minimal Genome Design Algorithms using Whole-Cell Models -- Tn-Core: Functionally Interpreting Transposon-Sequencing Data with Metabolic Network Analysis -- Genome-scale Metabolic Modeling of Escherichia coli and its Chassis Design for Synthetic Biology Applications -- A Systems Bioinformatics Approach to Interconnect Biological Pathways. .
520 _aThis second edition book provides complete coverage of the computational approaches currently used in Synthetic Biology. New chapters detail computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Computational Methods in Synthetic Biology, Second Edition aims to feature a broad overview of the research areas that can be met in the area of in silico Synthetic Biology.
650 0 _aBioinformatics.
650 0 _aBiotechnology.
650 0 _aBiology
_xTechnique.
650 1 4 _aBioinformatics.
650 2 4 _aBiotechnology.
650 2 4 _aBiological Techniques.
700 1 _aMarchisio, Mario Andrea.
_eeditor.
_0(orcid)0000-0002-5102-1069
_1https://orcid.org/0000-0002-5102-1069
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071608210
776 0 8 _iPrinted edition:
_z9781071608234
776 0 8 _iPrinted edition:
_z9781071608241
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2189
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-0822-7
912 _aZDB-2-PRO
999 _c5538
_d5538