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020 _a9781071626993
_9978-1-0716-2699-3
024 7 _a10.1007/978-1-0716-2699-3
_2doi
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072 7 _aPNFS
_2bicssc
072 7 _aSCI013010
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072 7 _aPNFS
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082 0 4 _a543.65
_223
245 1 0 _aMass Spectrometry for Metabolomics
_h[electronic resource] /
_cedited by Raúl González-Domínguez.
250 _a1st ed. 2023.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2023.
300 _aXV, 272 p. 56 illus., 51 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
341 0 _bTable of contents navigation
_2onix
341 0 _bSingle logical reading order
_2onix
341 0 _bShort alternative textual descriptions
_2onix
341 0 _bUse of color is not sole means of conveying information
_2onix
341 0 _bUse of high contrast between text and background color
_2onix
341 0 _bNext / Previous structural navigation
_2onix
341 0 _bAll non-decorative content supports reading without sight
_2onix
347 _atext file
_bPDF
_2rda
490 1 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2571
505 0 _aComprehensive and High-Throughput Method for Quantitative Fingerprinting of Phenolic Compounds -- Determination of Volatile Metabolites in Vinegars by Solid Phase Microextraction-Gas Chromatography-Mass Spectrometry (SPME-GC-MS) -- Determination of Volatile Metabolites in Vinegars by Stir Bar Sorptive Extraction-Gas Chromatography-Mass Spectrometry (SBSE-GC-MS) -- Discovery of Food Intake Biomarkers Using Metabolomics -- Metabolomic Characterization of the Antiproliferative Activity of Bioactive Compounds from Fruit By-Products Against Colon Cancer Cells -- Untargeted Metabolomics by Liquid Chromatography-Mass Spectrometry in Biomedical Research -- Untargeted Metabolomics for Disease-Specific Signatures -- Metabolomics Analysis of Blood, Urine, and Saliva Samples Based on Capillary Electrophoresis-Mass Spectrometry -- Capillary Electrophoresis-Mass Spectrometry for the Direct Analysis of Metabolites in Highly Saline Samples Using In-Capillary Preconcentration -- Chemical Derivatization to Enhance Capillary Electrophoresis Mass Spectrometric Analysis of Acidic Metabolites in Mammalian Cells -- Untargeted Metabolomics Based on Liquid Chromatography-Mass Spectrometry for the Analysis of Plasma and Erythrocyte Samples in Childhood Obesity -- Characterization of the Plasmatic and Erythroid Multi-Elemental Biodistribution in Childhood Obesity Using a High-Throughput Method for Size-Fractionation of Metal Species -- Analysis of Brain Metabolites Using Two Complementary Ultra-High Performance Liquid Chromatography Mass Spectrometry Methods -- Analysis of Cholesterol from the Liver Using Gas Chromatography-Mass Spectrometry -- Metabolomics Analysis of Aqueous Humor Based on Liquid Chromatography-Mass Spectrometry -- Analyses and Localization of Serotonin and L-DOPA in Ocular Tissues by Imaging Mass Spectrometry -- Isobaric Incorporation of C13-Histidine for the Assessment of Remyelination -- Isolation and Lipidomic Screening of Human Milk Extracellular Vesicles -- Mass Spectrometry-Based Untargeted Metabolomics and Lipidomics Platforms to Analyze Cell Culture Extracts -- Data Processing and Analysis in Mass Spectrometry-Based Metabolomics -- Data Processing and Analysis in Liquid Chromatography-Mass Spectrometry-Based Targeted Metabolomics -- Instrument-Agnostizing Methodology for Liquid Chromatography-Mass Spectrometry Systems.
520 _aThis detailed volume provides a comprehensive overview of state-of-the-art metabolomics methods based on mass spectrometry (MS), and their application in food, nutrition, and biomedical research. The chapters assembled herein cover hot topics related to sample preparation, chromatographic and electrophoretic separation, MS-based analysis, as well as data processing and analysis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mass Spectrometry for Metabolomics serves as a timely guide for chemists, biochemists, biologists, nutritionists, clinicians, and other experts working in the growing and exciting field of metabolomics.
532 8 _aAccessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com.
532 8 _aNo reading system accessibility options actively disabled
532 8 _aPublisher contact for further accessibility information: accessibilitysupport@springernature.com
650 0 _aMass spectroscopy.
650 0 _aBiochemistry.
650 0 _aMetabolism.
650 0 _aCell biology.
650 1 4 _aMass Spectrometry.
650 2 4 _aMetabolic Pathways.
700 1 _aGonzález-Domínguez, Raúl.
_eeditor.
_0(orcid)0000-0002-7640-8833
_1https://orcid.org/0000-0002-7640-8833
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781071626986
776 0 8 _iPrinted edition:
_z9781071627006
776 0 8 _iPrinted edition:
_z9781071627013
830 0 _aMethods in Molecular Biology,
_x1940-6029 ;
_v2571
856 4 0 _uhttps://doi.org/10.1007/978-1-0716-2699-3
912 _aZDB-2-PRO
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