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020 _a9781493999446
_9978-1-4939-9944-6
024 7 _a10.1007/978-1-4939-9944-6
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aSCI089000
_2bisacsh
072 7 _aPSAN
_2thema
082 0 4 _a612.8
_223
245 1 0 _aBasic Neurobiology Techniques
_h[electronic resource] /
_cedited by Nicholas J. D. Wright.
250 _a1st ed. 2020.
264 1 _aNew York, NY :
_bSpringer US :
_bImprint: Humana,
_c2020.
300 _aXII, 352 p. 129 illus., 106 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aNeuromethods,
_x1940-6045 ;
_v152
505 0 _aSemiconductor Quantum Dots for Visualization and Sensing in Neuronal Cell Systems -- Injection of Adeno-Associated Virus Containing Optogenetic and Chemogenetic Probes into the Neonatal Mouse Brain -- Guide to Transcranial Imaging of Sound-Evoked Activity in the Auditory Cortex of GCaMP6s Mice In Vivo -- A Novel Pre-Clinical Rat Model of Alzheimer’s Disease -- Using Zebrafish to Study and Visualize Barriers of the CNS -- Photometric Patch Electrode to Simultaneously Measure Neural Electrical Activity and Optical Signal in the Brain Tissue -- Patch-Clamp Fluorometry and Its Applications to the Study of Ion Channels -- Modeling Early-Onset Post-Ischemic Seizures in Adult and Aging Mice -- Modeling Psychological Trauma in Rats -- Extending the Life-Span of Acute Neuronal Tissue for Imaging and Electrophysiological Studies -- Confocal Imaging of Fast Flash Photolysis of Caged Compounds in Cultured Neurons -- Analysis of the Functional Statesof an Astrocyte Syncytium -- Assessment of Behavioral Dysfunction following Experimental Traumatic Brain Injury (TBI).
520 _aThis volume explores the latest techniques and improved methods used to study important neurobiological and associated neuropathological conditions. Chapters cover topics such as the application of semiconductor quantum dots as photostable fluorophores used for labeling and tracking; GCaMP6 transcranial imaging to monitor neural activity; the patch-clamping technique allowing simultaneous monitoring of membrane currents and optical signals; and quantifying behavioral dysfunction caused by traumatic brain injury (TBI). In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Basic Neurobiology Techniques is a valuable resource for novel and expert researchers interested in expanding their knowledge of this developing field. .
650 0 _aNeurosciences.
650 1 4 _aNeuroscience.
700 1 _aWright, Nicholas J. D.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9781493999439
776 0 8 _iPrinted edition:
_z9781493999453
776 0 8 _iPrinted edition:
_z9781493999460
830 0 _aNeuromethods,
_x1940-6045 ;
_v152
856 4 0 _uhttps://doi.org/10.1007/978-1-4939-9944-6
912 _aZDB-2-PRO
999 _c5335
_d5335