Clinical & Experimental Metastasis is an international, multidisciplinary journal devoted to the rapid publication of major fundamental advances in both basic and applied metastasis research. Clinical & Experimental Metastasis publishes Original Articles, Reviews, Short Communications, Commentaries and Letters to the Editor. The Journal's scope encompasses all aspects of metastasis research, whether laboratory-based, experimental or clinical and therapeutic. It covers such areas as molecular biology, pharmacology, tumor biology, and clinical cancer treatment (with all its subdivisions of surgery, chemotherapy and radio-therapy as well as pathology and epidemiology) insofar as these disciplines are concerned with the Journal's core subject of metastasis formation, prevention and treatment. While the emphasis is on speed of publication, with papers normally published within 2 weeks of acceptance, the Editors rigorously maintain refereeing standards to ensure only the highest quality research is selected for publication. Case studies are published only in exceptional circumstances and are better suited to journals that focus on case reports. Correlative clinical studies with small numbers of patients need to contain experimental validation of the findings. Experimental and laboratory-based research needs to provide a significant advance in knowledge, and should contain mechanistic functional insights. Validation of findings made with cell lines in experimental animal models is generally expected. Except in exceptional cases, verification of experimental data in at least two independent cell lines is generally required in order to exclude cell line-specific effects. .