The EMBO Journal publishes research papers of broad general interest, exceptional conceptual advance and functional insight. Studies range from molecular cell biology, to developmental biology and physiology, to ecology - selected without preference for specific experimental approaches or model systems. Submissions with authoritative referee reports from Review Commons or other journals are welcome and will be considered, where possible, without additional review. The journal publishes full-length Articles, Methods and Resources. These are complemented by authoritative Perspectives and Reviews, as well as Comments, Opinions and News & Views. Areas covered include, but are not limited to: Ageing Autophagy Biophysics Cancer Cell adhesion, Polarity and Cytoskeleton Cell cycle Cell death Chromatin, Epigenetics and Genomics Developmental biology DNA replication, repair and recombination Ecology Evolution Immunology and Host-pathogen interaction Membranes and transport Metabolism Microbiology Virology Molecular biology of disease Neuroscience Plant biology Post-translational modifications and proteolysis RNA biology Signal transduction Stem cells Structural biology Systems biology and multiomics Chemical and computational biology Transcription and Translation Protein biosynthesis and quality control Vascular biology.