Includes bibliographical references and index.

Front Matter -- Opening Address / S. Tamminga and M.W.A. Verstegen -- Words of welcome / A.J.M. Jansman -- Analytical methods for the analysis of antinutritional factors in legume seeds / L.C. Trugo and D. von Baer -- Technique to determine levels of soya bean lectin in feed samples and digesta samples collected in vivo / B.G. Miller , J. Thorpe , D. Patel , and H. Schuhe -- Specific-Immuno-(Chymo)Trypsin-Inhibitor-Assays for determination of (residual) activity of Bowman-Birk or Kunitz Soybean Trypsin Inhibitors / A. van Amerongen , V. Ostafe , M.M.T. Meijer , H. Gruppen , G. Meerdink , L.B.J.M. Berendsen , M. Koets , and J.H. Wickers -- Comparative study of condensed and hydrolyzable tannin interaction with isolated proteins and enzymes / W. Sandoval and A. Carmona -- Antinutritional factors and nutritive value of different cultivars of pea, chickpea and faba bean / C. Cerioli , L. Fiorentini , A. Prandini , and G. Piva -- Biochemical characterization of a trypsin-chymotrypsin inhibitor from Vigna radiata / A.H. Pande , N. Hajela , and K. Hajela -- Trypsin inhibitor and crude protein content of some New Zealand selections of chickpeas / G.P. Savage , K. Knowler , and D. Goulden -- Optimisation of protein extraction from feed and digesta samples and the subsequent measurement of ANFs in these samples / J. Thorpe , B.G. Miller , D. Patel , and H. Schulze -- Mode of action of the Kunitz trypsin and the Bowman-Birk proteinase inhibitors from soya bean against trypsins and chymotrypsins / J.K.P. Weder and A. Kind -- Analyses of antinutritional factors in rapeseed / C. Bjergegaard , S. Krogh Jensen , A. Quinsac , and H. Sorensen -- Mechanisms of indole formation resulting from glucobrassicin breakdown / K. Hrnèiøík and J. Velíšek -- Antinutritive factors in cool season legume seeds for human nutrition - with particular reference to chickpeas / G.P. Savage and H. Frøkiær -- ANFs in tropical legume seeds for human nutrition / R. Ali and M. Muzquiz -- Interaction of the bean ( Phaseolus vulgaris ) α-amylase inhibitors with human α-amylases: structural and functional aspects / V. Le Bcrre-Anton , V. Nahoum , M. Santimone , A. Barre , G. Marchis-Mouren , F. Payan , and P. Rougé -- Protein protease inhibitors: reflections on their net beneficial effects / Y. Birk -- The condensed tannin content of Bambara groundnut ( Vigna subterreanea L. Verdc) / J.O. Amarteifio , S.K. Karikari , and E. Moichubedi -- Proteinase inhibitors and oligosaccharides of redgram ( Cajanus cajan ) / V.H. Mulimani , S. Devendra , and K. Sudheendra -- Pro-nutritional factors in food: the cancer preventive potential of Brussels sprouts studied in human volunteers / H. Verhagen and G. van Poppel -- The effects of antinutritional factors in legume seed and rapeseed on ruminant nutrition / G.D. Hill and S. Tamminga -- Potential and limitations of in vitro gas methods for studying the effects of plant defensive compounds on rumen fermentation / H.P.S. Makkar , M. Blümmel , and K. Becker -- Effects of Lupinus alkaloids on in vitro rumen fermentation and their fate in the rumen / R. Aguiar , M. Wink , H.P.S. Makkar , M. Blümmel , and K. Becker -- Effects of antinutritional factors in rapeseed / L.D. Campbell and F. Schöne -- Food intake of growing and adult rats fed rapeseed meal detoxified by Rhizopus microsporus var. chinensis Schwertz / P. Rozan , C. Villaume , and L. Méjean -- Nutritional quality of toasted or dehulled and cold defatted rapeseed meal / P. Rozan , C. Villaume , J. Evrard , and L. Méjean -- Effects of rapeseed and rapeseed press cake with different glucosinolate content on the performance of growing pigs / F. Schöne , U. Kirchheim , and F. Tischendorf -- The effect of rapeseed and rapeseed press cake with different glucosinolate content on sows and their piglets / F. Schöne , M. Leiterer , and G. Jahreis -- Recent progress in the understanding of the mode of action and effects of antinutritional factors from legume seeds in non-ruminant farm animals / J.P. Lallès and A.J.M. Jansman -- The body metabolism of mammals can be adversely affected by enzyme inhibitors from legume seeds / G. Grant , S. Murray , E. Gravells , T.J. Duguid , S. Bardocz , and A. Pusztai -- Variability of pea protein and amino acid digestibility in growing pig / F. Grosjean , I. Williatte-Hazouard , B. Carrouée , C. Peyronnet , F. Skiba , and F. Gâtel -- Studies on the antinutritional effects of pea seed trypsin inhibitors using near-isogenic lines. 1. Production and chemical analysis of seed / T. Welham , S. Boisen , N. Canibe , M.S. Jensen , L. Bilham , and C. Domoney -- Studies on the antinutritional effects of pea seed trypsin inhibitors using near-isogenic lines. 2. Biological responses to variation in trypsin inhibitor activity / M.S. Jensen , S. Boisen , N. Canibe , T. Welham , and C. Domoney -- Duodenal passage of immunoreactive glycinin and β-conglycinin from soya bean in preruminant calves / J.P. Lallès , A. Huet , L. Quillien , G. W. Plumb , E.N.C. Mills , M.R.A. Morgan , and R. Toullec -- The influence of tannins on phytase efficiency in growing pigs / J. Salobir , K. Salobir , M. Štruklec , and B. Kostanjevec -- Is lupin gramine (indole alkaloid) an antinutritive factor for pigs? / J. Wasilewko , L. Buraczewska , and R. Lechowski -- Nutritional and nutritive characteristics of some soya protein sources for early weaned piglets / J. Decuypere , N. Dierick , and E. Vereecke -- Histological alterations to the pancreas and the intestinal tract produced by kabuli and desi chick pea ( Cicer arietinum L.) diets in growing chicks / R. Elices , A. Viveros , M. Pizarro , A. Brenes , and I. Arija -- Pancreatic responses of mammals to dietary bioactive factors are influenced by age and diet / G. Grant , J.E. Edwards , W.C. Buchan , C. Coull , N.H. McKenzie , S. Bardocz , and A. Pusztai -- Development of an experimental model to measure digestibility of soya bean antinutritional factors in vivo in the 4 week old weaned pig / B.G. Miller , J. Thorpe , D. Patel , and H. Schuhe -- Use of spray-dried bovine blood plasma as receptor-analogue in piglet rations containing Phaseolus vulgaris beans / C. Van Nevel , M. Seynaeve , H. Vermeirsch , H. Lauwers , E. Van Driessche , and R. De Wilde -- Canavalia ensiformis affects survival and body weight and composition of Sitophilus oryzae adults / A. Gómez-Sotillo and A. Carmona -- Interaction of bean tannins with Phaseolus vulgaris proteins / G. Borges , A. Levy-Benshimol , and A. Carmona -- (And) nutritional effect of α-galactosides? / A. Veldman , H. Enting , and A.C.J.M. Smulders -- Raw and processed full-fat soya beans in diets for broilers and growing or fattening pigs / W. Wetscherek -- Intestinal absorption of D-galactose in rats fed extruded Pisum sativum , and Phaseolus vulgaris / F. Marzo , E. Orúe , J. Butrón , F. Ibáñez , and R. Alonso -- Effects of dietary soya bean and cowpea on gut morphology and faecal composition in creep and noncreep-fed pigs / M.O. Makinde , E. Umapathy , B.T. Akingbemi , K.T. Mandisodza , and E. Skadhauge -- A new oral sensitization model in rats to food proteins and the importance of dietary control in oral sensitization with soy / L.M.J. Knippels , A.M. Penninks , S. Spanhaak , and G.F. Houben -- Effects of soya trypsin inhibitors on faecal nutrient digestibility and nitrogen retention in young piglets / A.J.M. Jansman , J. Huisman , G.M. Beelen , and J. Wiebenga -- Comparison of three methods for the measurement of the endogenous N-flow at the terminal ileum of pigs, as affected by dietary quebracho extract / C.A. Steendam , E.J. de Jong , S. Mattuzzi , and G.H. Visser -- Effect of soya carbohydrate fractions on the ileal digestibility and endogenous flow of nitrogen in veal calves / J.M.A.J. Verdonk , G.M. Beelen , A.J.M. Jansman , and J. Huisman -- Effect of processing of soya protein on the ileal digestibility and endogenous flow of nitrogen in veal calves / J.M.A.J. Verdonk , G.M. Beelen , A.J.M. Jansman , and J. Huisman -- Recent developments on the improvement of ANF levels in legume seeds by breeding / J.P.F.G. Helsper -- Transgenic plants: the need for nutritional testing / G. Grant , T.J. Murray , S.P. Worton , S. Bardocz , and A. Pusztai -- Genetic manipulation of enzyme inhibitors in pea seeds / C. Domoney and T.

Welham -- Use of enzymes and process technology to inactivate antinutritional factors in legume seeds and rapeseed / G.L. Campbell and A.F.B. van der Poel -- Variation of alkaloids, alkaloids esters, phytic acid and phytase activity in germinated seed of Lupinus albus and L. luteus / M. Muzquiz , M.M. Pedrosa , C. Cuadrado , G. Ayet , C. Burbano , and A. Brenes -- Effects of chemical treatments, pelleting or extrusion on the elimination of antinutritional factors in Phaseolus vulgaris beans / H. Beumer , A.J. Vooijs , A. Jurgens , and J.F.C. van Maanen -- Modelling of the product quality of soya beans during steaming / R. van den Hout , G. Meerdink , D. van Zuilichem , and K. van ’t Riet -- Heat processing of rapeseed meal containing diets:effects on growth performance and ileal nutrient digestibility in pigs / R. De Schrijver and J. Vande Ginste -- Variations in antinutritional factors at different development stages in seed of Phaseolus vulgaris and Erythrina americana / A. Sotelo and B. Lucas -- Effect of germination on the inositol phosphate content and phytase activity in under-utilised legume seeds grown in Nigeria / H.A Oboh , A. Brenes , C. Burbano , C. Cuadrado , C. Centeno , M. Muzquiz , G. Ayet , M.M. Pedrosa , and A.U. Osagie -- The effect of germination and extrusion on the nutritional quality of peas ( Pisum sativum L. cv. Ballet) / E. Orúe , J. Butrón , F. Ibáñez , R. Alonso , and F. Marzo -- Physicochemical changes in Pisum sativum L. and Phaseolus vulgaris L. proteins induced by extrusion cooking / R. Alonso , E. Orúe , J. Butrón , and F. Marzo -- Cultivar differences and effect of cooking on moong bean seed antinutrients and in vitro digestibility of protein and starch / S. Jood and S. Sehgal -- The inactivation of legume seed haemagglutinin and trypsin inhibitors by boiling / H. Leontowicz , H. Kostyra , M. Leontowicz , and G.W. Kulasek -- Reduction of glucosinolates and sinapine in rapeseed by technical treatment: Description of the technical procedure and effectiveness evaluation / H. W. Lucht -- Effect of untreated and hydrothermally treated rapeseed in feeding of laying hens / H. Jeroch , S. Dänicke , and J. Brettschneider -- The effect of residual tannins and phytic acid in cooked legumes on apparent protein digestibility in the intestinal tract of broiler chicks / A.D. Ologhobo , J.I. Idowu , E.O. Iyaniwura , and A.A. Sadiq -- Antinutritional factors in raw and heat-treated cowpea ( Vigna unguiculata) and their effects on growth in weanling pigs / E. Umapathy , M.O. Makinde , K.H. Erlwanger , P.S. Makkar , K. Becker , and E. Skadhauge -- Degradation of phytate in peas by bioprocessing / M. Fredrikson , M. Larsson , A. Haikara , E. Lemola , A. Laitala , and A-S. Sandberg -- Expander processing of full-fat soya beans, a product development tool / D.J. van Zuilichem , W. Stolp , I. Wolters , and A.F.B. van der Poel -- Supplementation with carbohydrases of a soya bean meal-based rooster diet: effects on nitrogen retention and metabolisable energy / P.J.A.M. Weekers and R. De Schrijver -- Overview and recommendations for the future / G.D. Hill -- Closing comments / J. Huisman.

This publication contains the proceedings of the 4th International Workshop on Antinutritional Factors in Legume Seeds and Oilseeds held in Toledo, Spain on 8-10 March 2004. This series of meetings bring together experts working in this field of Science from throughout the world. A major feature of each conference session is an invited review, which outlines the advances that have been made in a particular area since the last meeting. A major factor that was considered at this meeting was the likely impact of plant genetic modification on the nutritional quality of their seeds for human and animal feeding. As an example already a number of legume species and rapeseed have been modified to improve the sulphur amino acid content of their seed and thus their protein quality. Besides the major grain legume species and rapeseed that had been discussed at previous meetings in this series number of crop products, as potential protein sources, for animal feeding, were considered for the first time. These included cottonseed meal, linseed meal, and sunflower seed meal. The potential of some new exotic crops from Mexico was also covered including Mexican species of the genus Lupinus and a Mexican plant from the same family as castor bean, which has a very high oil content but is usually toxic. Work from Cuba compared the nutritional characteristics of soybean with a range of tropical grain legume species, which have received little previous attention. A major change at this meeting was the greater consideration of the effects, both positive, and negative, of the consumption of these seeds for human nutrition. A major review on the development of allergnicity to legume seed in humans is included. There was also consideration of the potential role of antinutritional factors in reducing the growth of various types of tumour cells. The presented papers also suggest that the consumption of legume seed in the diet can potentially reduce serum cholesterol levels. Overall from the 5 conference sessions there are 52 papers. Of these 7 are major invited reviews on the current state of research in this important area for human and animal feeding.

English

Description based on print version record.