Aims and Scope Separation sciences, in all their various forms such as chromatography, field-flow fractionation, and electrophoresis, provide some of the most powerful techniques in analytical chemistry and are applied within a number of important application areas, including archaeology, biotechnology, clinical, environmental, food, medical, petroleum, pharmaceutical, polymer and biopolymer research. Beyond serving analytical purposes, separation techniques are also used for preparative and process-scale applications. The scope and power of separation sciences is significantly extended by combination with spectroscopic detection methods (e.g., laser-based approaches, nuclear-magnetic resonance, Raman, chemiluminescence) and particularly, mass spectrometry, to create hyphenated techniques. In addition to exciting new developments in chromatography, such as ultra high-pressure systems, multidimensional separations, and high-temperature approaches, there have also been great advances in hybrid methods combining chromatography and electro-based separations, especially on the micro- and nanoscale. Integrated biological procedures (e.g., enzymatic, immunological, receptor-based assays) can also be part of the overall analytical process. CHROMATOGRAPHIA will highlight new and fundamental developments in separation technologies and approaches, sorbent materials, mobile phases, sample preparation methods, and detection techniques, to improve the sensitivity, selectivity, efficiency and speed of separations. These can include hyphenated systems that integrate several unit operations within the analytical workflow (e.g., sample clean-up, separation, assay, detection). Advanced and complex applications of the separation sciences are welcome, provided they include clear novelty and have significance to the wider analytical community. It will also report advances in miniaturisation and the scaling down of systems to enable the analysis of smaller sample siz es and volumes and to allow the simultaneous screening of multiple compounds (i.e., -omics approaches). Preliminary data can be published, again provided there is sufficient novelty in the operations or their combination and the results will be beneficial for the readers of CHROMATOGRAPHIA and could inspire them to bring their own research to a higher level. CHROMATOGRAPHIA welcomes submissions that present significant scientific advances in any of these fields. Originality, novelty and scientific value are the key criteria of the Editors for selecting publications appropriate for CHROMATOGRAPHIA. Submission of papers describing the application of established methods or techniques to individual or small groups of compounds, or to an additional matrix/sample is discouraged. The language of the journal is English and it is the author’s responsibility to ensure the quality of English used in the submitted manuscript.