Cell-Based Assays Using iPSCs for Drug Development and Testing (Record no. 8355)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06441nam a22006495i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-0716-4530-7 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083719.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250501s2025 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781071645307 |
| -- | 978-1-0716-4530-7 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-0716-4530-7 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | TP248.13-248.65 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RS189-190 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | TCB |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI010000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | TCB |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 660.6 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Cell-Based Assays Using iPSCs for Drug Development and Testing |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Carl-Fredrik Mandenius, James A. Ross. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 2nd ed. 2025. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer US : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025. |
| 300 ## - online resource | |
| Extent | XI, 270 p. 68 illus., 61 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Table of contents navigation |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Single logical reading order |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Short alternative textual descriptions |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Use of color is not sole means of conveying information |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Use of high contrast between text and background color |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Next / Previous structural navigation |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | All non-decorative content supports reading without sight |
| Source | onix |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 2924 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Cell-Based Assays Using Derived Human Induced Pluripotent Cells in Drug Discovery and Development -- Using Human iPSC-Derived Astrocytes to Investigate Transcription Factor-Driven Astrocyte to Neuron Transdifferentiation -- Human Induced Pluripotent Stem Cell-Derived Definitive Endoderm Bulk Up and Hepatic Differentiation -- One-Step Differentiation of Human Induced Pluripotent Stem Cells into Podocytes -- Human Pluripotent Stem Cell Expansion in Stirred Tank Bioreactors -- Co-Cultures of Human Induced Pluripotent Stem Cell-Derived Neurons, Astrocytes, and Microglia for Modeling Neurodegenerative Diseases -- A Robust Protocol for Pluripotent Stem Cell Modeling of 3D Chamber-Like Cardiac Organoids -- Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells for the Study of Macular Degeneration -- Human Pluripotent Stem Cell-Derived Endothelial Cells in Disease Modeling and Drug Screening -- Toxicity Testing Using Organoids Made from Human Induced Pluripotent Stem Cells Engineered to Report Oxidative Stress -- Modeling Human Liver Steatosis in Induced Pluripotent Stem Cell-Derived Liver Spheres -- Utility of Induced Pluripotent Stem Cell-Based Microphysiological Systems for Drug Development and Testing -- Compound Testing of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using Multi-Well Microelectrode Arrays -- Methodology and Practice for Studying Crosstalk between 3D Human Tissue Models in Pneumatically Actuated Multi-Organ-on-Chip Systems -- Spheroid Formation and Easy and Stable Control of Stromal Cells Using Multi-Inlet Spheroid Generator -- Engineered Hydrogels for 3D Cell Culture and Bioprinting of Human Induced Pluripotent Stem Cell-Derived Neuroepithelial Stem Cells -- A Non-Destructive, Image Analysis Method for Evaluating Pigmentation in Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells -- Evaluating the Effect of Drug Compounds on Cardiac Spheroids Using the Cardiac Cell Outgrowth Assay in a Microphysiological System -- High Content Analysis of Mitochondrial Function in Induced Pluripotent Stem Cell-Derived Neurons. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This up-to-date volume presents a set of differentiation and assay protocols useful to researchers involved in disease modeling, drug discovery, and the cell biology of a variety of tissues. The book begins with chapters on culture of induced pluripotent stem cells (iPSCs) and iPSC-derived cells with detailed protocols for culturing and differentiation of iPSC-derived endoderm, hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, neurons, and astrocytes. This is accompanied by newer protocols for the use of 3D cultures in assays adapted for drug development purposes, with new techniques such as high content analysis and microphysiological systems. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cell-Based Assays Using iPSCs for Drug Development and Testing, Second Edition serves as an ideal guide for scientists working to develop human iPSC-derived cellular models for drug discovery, efficacy, and safety purposes. |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | No reading system accessibility options actively disabled |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | Publisher contact for further accessibility information: accessibilitysupport@springernature.com |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biological assay. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Stem cells. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Assay Systems. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Stem Cell Biology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mandenius, Carl-Fredrik. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ross, James A. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071645291 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071645314 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071645321 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 2924 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-0716-4530-7">https://doi.org/10.1007/978-1-0716-4530-7</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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