In Vitro Toxicology Systems (Record no. 8119)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04079nam a22005055i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-4939-0521-8 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083715.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 140430s2014 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781493905218 |
| -- | 978-1-4939-0521-8 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4939-0521-8 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM300-666 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MMG |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED071000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MKG |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | In Vitro Toxicology Systems |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Anna Bal-Price, Paul Jennings. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2014. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer New York : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2014. |
| 300 ## - online resource | |
| Extent | XXI, 583 p. 64 illus., 54 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Pharmacology and Toxicology, |
| International Standard Serial Number | 1940-6053 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | The Past, Present and Future of Chemical Risk Assessment.- In Vitro Systems for Hepatotoxicity Testing -- In Vitro Methods for Cardiotoxicity Testing -- Renal Cell Culture -- Cellular Models for In Vitro Lung Toxicology -- In Vitro Developmental Neurotoxicity Testing: Relevant Models and Endpoints -- Blood Brain Barrier In Vitro Models and Their Applications in Toxicology -- Ocular Toxicity -- In Vitro Models for Ototoxic Research -- Dermal Toxicity: Skin Sensitization -- Immunotoxicity -- Reproductive Toxicity -- Evaluating Endocrine Disruption In Vitro -- Current and Emerging In Vitro Methods for Genotoxicity and Carcinogenicity -- Use of Induced Pluripotent Stem Cells in Drug Toxicity Screening -- Human Stem/Progenitor Cell-Based Assays for Neurodevelopmental Toxicity Testing -- High Content Imaging Approaches for In Vitro Toxicology -- Application of Omics Technologies to In Vitro Toxicology -- Stress Response Pathways -- Translational Biomarkers, In Vitro and In Vivo -- Nanotoxicology -- Consideration of Metabolism in In Vitro Cellular Systems -- In Vitro Approaches to Predictive Biokinetics -- Extrapolating In Vitro Results to Predict Human Toxicity -- Considerations in the Development of In Vitro Toxicity Testing Methods Intended for Regulatory Use. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism, and in vitro in vivo extrapolation. The book also addresses biological processes such as stress response pathways and mechanistic biomarkers and how these can be uncovered and measured using high content approaches. Reliable and authoritative, In Vitro Toxicology Systems will be of benefit not only to students, scientists, and regulators working in the field of chemical safety assessment but also to a wider scientific audience. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine |
| General subdivision | Research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biology |
| General subdivision | Research. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biomedical Research. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bal-Price, Anna. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jennings, Paul. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493905201 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493905225 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493954803 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Pharmacology and Toxicology, |
| International Standard Serial Number | 1940-6053 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-4939-0521-8">https://doi.org/10.1007/978-1-4939-0521-8</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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