Teratogenicity Testing (Record no. 8040)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 07252nam a22006255i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-0716-3625-1 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083714.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240129s2024 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781071636251 |
| -- | 978-1-0716-3625-1 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-0716-3625-1 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QH491-492 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSC |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI072000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSC |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 571.8 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Teratogenicity Testing |
| Medium | [electronic resource] : |
| Remainder of title | Methods and Protocols / |
| Statement of responsibility, etc. | edited by Luís Félix. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 2nd ed. 2024. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer US : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - online resource | |
| Extent | XVI, 627 p. 113 illus., 96 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Table of contents navigation |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Single logical reading order |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Short alternative textual descriptions |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Use of color is not sole means of conveying information |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Use of high contrast between text and background color |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | Next / Previous structural navigation |
| Source | onix |
| 341 0# - ACCESSIBILITY CONTENT | |
| Textual assistive features | All non-decorative content supports reading without sight |
| Source | onix |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 2753 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Updating an Overview of Teratology -- Guidelines on Development Toxicity Tests: Brief Insights -- Development Features on the Selection of Animal Models for Teratogenic Testing -- Virus as Teratogenic Agents -- The Future of the Teratogenicity Testing -- The First Steps on AOPs' Concepts, Development, and Applications in Teratology -- Machine Learning to Predict Teratogenicity: Theory and Practice -- Human Pluripotent Stem Cell-Based Assays to Predict Developmental Toxicity -- Developmental Toxicity Using the Rat Whole Embryo Culture -- A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs -- Teratogenic Effects of Drugs on Primary Lymphocytes Assessed by Flow Cytometry -- Assessment of the Teratogenic Effect of Drugs on the Chicken Embryo -- Daphnia magna as a Model Organism to Predict the Teratogenic Effect of Different Compounds -- Caenorhabditis elegans as an In Vivo Model Organism to Elucidate Teratogenic Effects -- Enduring Ethanol-Induced Behavioral Alterations in Caenorhabditis elegans after Developmental Lead Exposure -- Exploration of Teratogenic and Genotoxic Effects on Model Organism Drosophila melanogaster -- Ecotoxicological Assessment of Seaweed-Based Crop Biostimulant on Earthworm Eudrilus eugeniae Kinb -- Evaluation of the Ecotoxicology of Seaweed-Based Biopesticide Used in Combat of the Polyphagous Pest Using Eudrilus eugeniae Kinb -- Biochemical Studies to Understand Teratogenicity and Lethality Outcomes in Modified-FETAX -- Bioinformatics Methods for Transcriptome Analysis on Teratogenesis Testing -- Angiogenesis Assay for Live and Fixed Zebrafish Larvae -- High-Resolution Respirometry for the Assessment of Teratogenic Chemicals -- A Stereological Approach to Quantify Immunohistochemical Staining in Zebrafish Larvae -- Whole-Mount Immunohistochemical and Immunofluorescence Assays in Zebrafish Embryos -- Assessment of Developmental Neurotoxicity Using Semi-Automatic Behavior Analysis System for Zebrafish -- Behavioral Profiling of Zebrafish (Danio rerio) Larvae: Activity, Anxiety, Avoidance, and Startle Response -- Alcian Blue Staining for Chondrocranium Development in Zebrafish -- Protocol of Geometric Morphometrics for Teratogenicity Testing -- Biochemical Markers for Liver Injury in Zebrafish Larvae -- Cortisol Quantification for Assessing Stress-Induced Changes in Zebrafish Larvae -- Metabolomic Fingerprint Assay in Zebrafish Embryos -- Alkaline Comet Assay to Assess Genotoxicity in Zebrafish Larvae -- A Chromogenic Quantification of Protein Expression in Zebrafish Larvae -- Confocal Microscopy Technique in Teratogenicity Testing Using Zebrafish (Danio rerio) Embryos as Model -- Whole-Mount RNA In Situ Hybridization of Zebrafish Embryos -- Quantitative Real-Time PCR Method to Evaluate Gene Expression in Zebrafish Embryos -- Microarray Analysis to Determine Gene Expression Changes in Zebrafish Embryos -- Cell-Free DNA and Next-GenerationSequencing for Prenatal Diagnosis. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This fully updated volume collects laboratory techniques and tests to assess the risks to embryo-fetal development from drug exposure during early developmental stages. Beginning with a section detailing basic principles of teratogenicity, the book continues with application of in vitro models for teratogenic screening to predict toxicity in embryonic animals and humans, as well as a variety of well-established in vivo animal model tests, which offer solutions for evaluating the efficacy and the teratogenicity of compounds in preclinical trials before human safety testing. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Teratogenicity Testing: Methods and Protocols, Second Edition serves as an ideal guide to tests that can be performed in cells, organs, tissues, and animal models for evaluating toxicity and/or safety of compounds in early developmental stages with the goal of estimating, preventing, or minimizing the teratogenic potential of drugs. |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | No reading system accessibility options actively disabled |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | Publisher contact for further accessibility information: accessibilitysupport@springernature.com |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Developmental biology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Embryology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Developmental Biology and Stem Cells. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medical Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Embryology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Félix, Luís. |
| Relator term | editor. |
| Authority record control number or standard number | (orcid)0000-0001-9870-6666 |
| Real World Object URI | https://orcid.org/0000-0001-9870-6666 |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071636244 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071636268 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071636275 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 2753 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-0716-3625-1">https://doi.org/10.1007/978-1-0716-3625-1</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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