Hepatitis C Protocols (Record no. 7640)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 07876nam a22005055i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-59259-260-9 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083707.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 100301s1998 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781592592609 |
| -- | 978-1-59259-260-9 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1385/0896035212 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC1-1245 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJC |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED022000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJC |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Hepatitis C Protocols |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Johnson Y. N. Lau. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 1998. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Totowa, NJ : |
| Name of producer, publisher, distributor, manufacturer | Humana Press : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 1998. |
| 300 ## - online resource | |
| Extent | XXI, 621 p. 171 illus. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Medicine, |
| International Standard Serial Number | 1940-6037 ; |
| Volume/sequential designation | 19 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Detection of Anti-HCV in Serum -- Detection of Anti-GOR Antibodies in HCV Infection -- Confirmation of HCV Antibodies by the Line Immunoassay INNO-LIA HCV Ab III -- Detection and Quantitation of HCV in Serum -- Detection of HCV RNA in Serum by Reverse Transcriptase-PCR and Radiolabeled Liquid Hybridization -- Detection of HCV RNA in Serum by Reverse Transcription Polymerase Chain Reaction (RT-PCR) -- The AMPLICOR® HCV Tests for the Detection and Quantitation of Serum or Plasma HCV RNA -- Quantification of HCV RNA in Clinical Specimens by Branched DNA (bDNA) Technology -- Quality Control of the Polymerase Chain Reaction -- Preparation of Genotype-Specific HCV RNA Transcripts for Assessing HCV Detection and Quantification Assays -- Detection of HCV in Liver Tissue -- Detection of HCV RNA in Formalin-Fixed, Paraffin-Embedded Liver Tissue by RT-PCR -- Quantification of HCV RNA in Liver Tissue by bDNA Assay -- HCV Genotypes -- Hepatitis C Virus -- Molecular Evolutionary Analysis -- Genotyping by Type-Specific Primers That Can Type HCV Types 1–6 -- Genotyping Hepatitis C Virus by Type-Specific Primers for PCR Based on NS5 Region -- Determination of HCV Genotypes by RFLP -- HCV Genotyping by the Line Probe Assay INNO-LiPA HCV II -- Serological Genotyping Using Synthetic Peptides Derived from the NS4 Region -- Determination of HCV Quasispecies by Cloning and Sequencing -- Detection of Hepatitis C Virus Quasispecies Heterogeneity by Single-Strand Conformational Polymorphism -- Hepatitis C Virus Heteroduplex Tracking Assay -- Detection of HCV In Situ -- In Situ Detection of HCV -- In Situ Detection of Hepatitis C Viral Antigens -- In Situ Hybridization and the Detection and Localization of HCV RNA -- The In Situ Detection of PCR-Amplified Hepatitis C RNA -- lmmunoelectron Microscopic Characterization ofHCV -- Molecular Biologic Characterization -- Cloning and Assembly of Complex Libraries of Full-Length HCV cDNA Clones -- Use of the Vaccinia Virus/T7 Expression System for Studying HCV Protein Processing -- Use of a Discistronic Vector for the Quantitation of HCV IRES Activity -- Expression and Dimerization of Hepatitis C Virus Core Protein in E. coli -- Expression and Characterization of the HCV NS2 Protease -- Expression and Characterization of HCV NS3 Protease -- Expression and Characterization of the HCV NS3 Helicase Domain -- Hepatitis C Virus RNA-Dependent RNA Polymerase (NS5B Polymerase) -- Detection and Molecular Cloning of the Extreme 3?-End of HCV -- In Vitro Stability of Hepatitis C Virus RNA -- Methods for the Study of Sequence-Specific Binding of Proteins to the HCV RNA Genome -- HCV-Specific Immunologic Response -- Role of Immune Response in HCV -- Determination of Hepatitis C Virus-Specific CD4+ T-Cell Activity in PBMC -- Measurement of HCV-Specific CD8+ Cytotoxic T-Cell Activities in the Peripheral Blood by Europium Release Assay -- Determination of HCV-Specific Bulk CD8+ Activity in Liver -- Characterization of HCV-Specific Cytotoxic T-Lymphocytes from Liver Tissue -- Production of Human Monoclonal Antibodies to Hepatitis C Virus and Their Characterization -- In Vitro Culture Model -- Specific Detection of Negative Strand RNA of Hepatitis C Virus Using Chemical RNA Modification -- Strand-Specific rTth RT-PCR for the Analysis of HCV Replication -- Cell Culture Systems for the Detection of HCV Infection -- Replication and Detection of Hepatitis C Virus in Liver-Derived Cell Lines -- Primary Human Hepatocyte Culture for the Study of HCV -- A Cultivation Method for Highly Differentiated Primary Chimpanzee Hepatocytes Permissive for Hepatitis C Virus Replication -- Construction ofRecombinant Viral Vectors for the Expression of HCV Genes -- Construction of Recombinant Vaccinia Virus Expressing HCV Genes -- Construction of Recombinant Adeno-Associated Virus (AAV) -- Production of Replication-Deficient Adenovirus Recombinants -- Generation of Recombinant Herpes Simplex Virus Ampiicons -- Construction of Recombinant Sindbis-Based Expression Vectors for the Study of HCV Genes and Their Products -- In Vivo Models -- The Chimpanzee Model -- Liver Transplantation as a Model to Study Hepatitis C Virus Infection. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In Hepatitis C Protocols, Johnson YN Lau and his expert collaborators present cutting-edge techniques for study of the hepatitis C virus infection and its disease, hepatitis C, which afflict an estimated 170 million people worldwide. The methods range from the detection of anti-HCV in serum and HCV in liver tissue, to HCV genotyping and the detection and quantification of HCV in serum. In addition to these key protocols, the authoritative contributors also evaluate recombinant proteins in immunological test systems, including the identification of important antigenic epitopes, antibodies, and recombinant antigens. Molecular and immunological techniques to study this virus and its infection, as well as animal models and recombinant virus technology commonly used to express hepatitis C viral proteins, are also developed. Hepatitis C Protocols summarizes the state-of-the-art in today's research and understanding of the virology of hepatitis C virus. The methods and systems detailed in this book will play a key role in the development of more effective antivirals, in the development of vaccines, and in a deeper understanding of viral replication strategies, viron structure, and the mechanisms of viron assembly and release. A valuable new standard resource for all researchers and clinicians, Hepatitis C Protocols leads the way toward improved prevention, diagnosis, and treatment of viral hepatitis C. |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | Accessibility summary: This PDF is not accessible. It is based on scanned pages and does not support features such as screen reader compatibility or described non-text content (images, graphs etc). However, it likely supports searchable and selectable text based on OCR (Optical Character Recognition). Users with accessibility needs may not be able to use this content effectively. Please contact us at accessibilitysupport@springernature.com if you require assistance or an alternative format. |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | Inaccessible, or known limited accessibility |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | No reading system accessibility options actively disabled |
| 532 8# - ACCESSIBILITY NOTE | |
| Summary of accessibility | Publisher contact for further accessibility information: accessibilitysupport@springernature.com |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Diseases. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Diseases. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lau, Johnson Y. N. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9780896035218 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781489943477 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781489943484 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Medicine, |
| International Standard Serial Number | 1940-6037 ; |
| Volume/sequential designation | 19 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1385/0896035212">https://doi.org/10.1385/0896035212</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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