Cell Cycle Checkpoints (Record no. 7533)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05020nam a22004815i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-61779-273-1 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083705.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 110825s2011 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781617792731 |
| -- | 978-1-61779-273-1 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-61779-273-1 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QH573-671 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSF |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI017000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSF |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 571.6 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Cell Cycle Checkpoints |
| Medium | [electronic resource] : |
| Remainder of title | Methods and Protocols / |
| Statement of responsibility, etc. | edited by Willis X. Li. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2011. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Totowa, NJ : |
| Name of producer, publisher, distributor, manufacturer | Humana Press : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2011. |
| 300 ## - online resource | |
| Extent | X, 307 p. 68 illus. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 782 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Studying G2 DNA Damage Checkpoints using the Fission Yeast Schizosaccharomyces pombe -- Studying S-phase DNA Damage Checkpoints using the Fission Yeast Schizosaccharomyces pombe -- Methods for Studying the G2 DNA Damage Checkpoint in Mammalian Cells -- Evaluating Spindle Assembly Checkpoint Competence in Mouse Oocytes using Immunoblotting -- Analysis of Changes in Protein Level and Subcellular Localization during Cell Cycle Progression using the Budding Yeast Saccharomyces cerevisiae -- Studying Cell Cycle Checkpoints using Drosophila Cultured Cells -- In Vivo Live-Analysis of Cell Cycle Checkpoints in Drosophila Early Embryos -- Using Drosophila Larval Imaginal Discs to Study Low Dose Radiation-induced Cell Cycle Arrest -- Screening for Radiation Sensitizers of Drosophila Checkpoint Mutants -- Study of Cell Cycle Checkpoints using Xenopus Cell-free Extracts -- Analyzing DNA Replication Dynamics of Genotoxin-Treated Cells Using Velocity Sedimentation -- Methods For Studying Checkpoint Kinases – Chk1 -- A Human Cell Extract-Based Assay for the Activation of ATM and ATR Checkpoint Kinases -- Analyzing p53 regulated DNA Damage Checkpoints by Flow Cytometry -- Using Drosophila S2 Cells to Measure S phase-Coupled Protein Destruction via Flow Cytometric Analysis -- Assessing G1-to-S-phase Progression After Genotoxic Stress -- Indirect Immunofluorescence for Monitoring Spindle Assembly and Disassembly in Yeast -- Detecting Recruitment of DNA Damage Response Factors through the eChIP Approach -- Methods to Study Cancer Therapeutic Drugs that Target Cell Cycle Checkpoints. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Cell cycle checkpoints control the fidelity and orderly progression of eukaryotic cell division. By controlling the orderly progression of critical cell cycle events such as DNA replication and chromosome segregation and ensuring proper repair of damaged DNA, cell cycle checkpoints function to ensure genome integrity. Mechanisms of checkpoint controls are not only the research focus of investigators interested in mechanisms that regulate the cell cycle, but are also the interests of researchers studying cancer development as it is increasingly clear that loss of cell cycle checkpoints, which leads to genomic instability as a result, is a hallmark of tumorigenesis. Cell Cycle Checkpoints: Methods and Protocols provides detailed descriptions of methodologies currently employed by researchers in the field, including those commonly used in the mammalian, yeast, C. elegans, Drosophila, and Xenopus model systems. Each chapter describes a specific technique or protocol, such as a method to induce cell cycle checkpoints in a particular model system, to synchronize a population of cells to allow observations of cell cycle progression, to identify genes involved in checkpoint regulation, and to study particular protein components of cell cycle checkpoint pathways. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Cell Cycle Checkpoints: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further our knowledge of this essentialfield. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cytology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cytology |
| General subdivision | Technique. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Biology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cytological Techniques. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Willis X. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781617792724 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781617792748 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493961818 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 782 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-61779-273-1">https://doi.org/10.1007/978-1-61779-273-1</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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