In Silico Tools for Gene Discovery (Record no. 7357)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04263nam a22004695i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-61779-176-5 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083702.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 110720s2011 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781617791765 |
| -- | 978-1-61779-176-5 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-61779-176-5 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RB155-155.8 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MFN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED107000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MFN |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.042 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | In Silico Tools for Gene Discovery |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Bing Yu, Marcus Hinchcliffe. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2011. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Totowa, NJ : |
| Name of producer, publisher, distributor, manufacturer | Humana Press : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2011. |
| 300 ## - online resource | |
| Extent | XI, 365 p. 110 illus., 3 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 760 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Accessing and Selecting Genetic Markers from Available Resources -- Linkage Analysis -- Association Mapping -- The ForeSee (4C) Approach for Integrative Analysis in Gene Discovery -- R Statistical Tools for Gene Discovery -- In Silico PCR Analysis -- In Silico Analysis of the Exome for Gene Discovery -- In Silico Knowledge and Content Tracking -- Application of Gene Ontology to Gene Identification -- Phenotype Mining for Functional Genomics and Gene Discovery -- Conceptual Thinking for In Silico Prioritization of Candidate Disease Genes -- Web Tools for the Prioritization of Candidate Disease Genes -- Comparative View of In Silico DNA Sequencing Analysis Tools -- Mutation Surveyor: An In Silico Tool for Sequencing Analysis -- In Silico Searching for Disease-Associated Functional DNA Variants -- In Silico Prediction of Transcriptional Factor Binding Sites -- In Silico Prediction of Splice-Affecting Nucleotide Variants -- In Silico Tools for qPCR Assay Design and Data Analysis -- RNA Structure Prediction -- In Silico Prediction of Post-Translational Modifications -- In Silico Protein Motif Discovery and Structural Analysis. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | As functional genomics has become one of the major focuses in molecular biology, the need for more sophisticated tools to assist in the identification of the functionality of undefined genes and the correlation of DNA variants with a particular phenotype has increased greatly. In Silico Tools for Gene Discovery collects many common and useful in silico tools available today. The volume begins by investigating locus mapping information on linkage analysis, association mapping, integrative analysis, and exome analysis as well as tools for DNA marker selection, in silico PCR, and statistical analysis. It continues with a section on gene discovery from a defined locus, including gene prioritization, knowledge tracking, and data mining, and concludes with several useful in silico tools presented for the functional characterization of genes, which include DNA sequencing analysis, variant characterization, as well as RNA and protein analysis. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, step-by-step, readily reproducible protocols, and vital notes on troubleshooting and avoiding known pitfalls. Resourceful and easy to follow, In Silico Tools for Gene Discovery seeks to facilitate scientists with further key research on locus mapping, to accelerate gene identification, and to help ascertain the functionality of DNA variation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medical genetics. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medical Genetics. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yu, Bing. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hinchcliffe, Marcus. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781617791758 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781617791772 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493961887 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 760 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-61779-176-5">https://doi.org/10.1007/978-1-61779-176-5</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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