Hypertension (Record no. 7143)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05445nam a22004575i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-59259-850-2 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083658.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 100301s2005 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781592598502 |
| -- | 978-1-59259-850-2 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1385/1592598501 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC666-701.2 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJD |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED010000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJD |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.12 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Hypertension |
| Medium | [electronic resource] : |
| Remainder of title | Methods and Protocols / |
| Statement of responsibility, etc. | edited by Jérôme P. Fennell, Andrew H. Baker. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2005. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Totowa, NJ : |
| Name of producer, publisher, distributor, manufacturer | Humana Press : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2005. |
| 300 ## - online resource | |
| Extent | XVI, 502 p. 98 illus. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Medicine, |
| International Standard Serial Number | 1940-6037 ; |
| Volume/sequential designation | 108 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Models Of Hypertension -- Congenic/Consomic Models of Hypertension -- Mouse Knockout Models of Hypertension -- Production of Transgenic Models in Hypertension -- Measuring Blood Pressure in Small Laboratory Animals -- Assessment Of Free Radicals In Endothelial Dysfunction -- Analysis of Superoxide Anion Production in Tissue -- Measurement of Vascular Reactive Oxygen Species Production by Chemiluminescence -- A Guide to Wire Myography -- Nucleic Acid Techniques -- Selection of Candidate Genes in Hypertension -- Genome-Wide Scanning With SSLPs in the Rat -- Extraction of RNA From Cells and Tissue -- Single-Strand Conformational Polymorphism Analysis -- Single-Nucleotide Polymorphism Genotyping for Disease Association Studies -- Denaturing High-Performance Liquid Chromatography Using the WAVE DNA Fragment Analysis System -- TaqMan Real-Time PCR Quantification Conventional and Modified Methods -- Generation of High-Sensitivity Antisense cDNA Probes by Asymmetric PCR -- New Advances in Microarrays Finding the Genes Causally Involved in Disease -- Pharmacogenetics and Pharmacogenomics -- Proteins And Proteomics -- Determination of the Endogenous Nitric Oxide Synthase Inhibitor Asymmetric Dimethylarginine in Biological Samples by HPLC -- Proteomic Approaches in the Analysis of Hypertension -- Gene Transfer -- Gene Transfer in Endothelial Dysfunction and Hypertension -- Nonviral Gene Delivery Methods in Cardiovascular Diseases -- Construction and Characterization of Helper-Dependent Adenoviral Vectors for Sustained In Vivo Gene Therapy -- Adenovirus-Mediated Gene Transfer In Vivo An Approach to Reduce Oxidative Stress -- Gene Therapy for Hypertension -- Modulation of Gene Expression by RNAi -- In Vivo Biopanning -- Stem Cells -- Cardiomyocytes Derived From Embryonic Stem Cells -- Bioinformatics -- In Silico andWet-Bench Identification of Nuclear Matrix Attachment Regions -- Biomedical Informatics Methods in Pharmacogenomics. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Our understanding of the pathogenesis of hypertension and the development of new therapies for its management have each proven to be directly dependent on the availability and application of novel molecular biological methodologies. In Hypertension: Methods and Protocols, a panel of recognized experts from key institutions around the world describes in step-by-step detail many new and essential molecular techniques for cardiovascular hypertension research. The methods presented range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using adenoviral and nonviral (polymers, liposomes, and antisense agents) vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. A review of bioinformatic resources for pharmacogenomics describes the application of in silico strategies to identify nuclear matrix attachment regions. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Hypertension: Methods and Protocols offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cardiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cardiology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fennell, Jérôme P. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Baker, Andrew H. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781588293237 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781617374937 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Medicine, |
| International Standard Serial Number | 1940-6037 ; |
| Volume/sequential designation | 108 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1385/1592598501">https://doi.org/10.1385/1592598501</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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