In Silico Methods for Predicting Drug Toxicity (Record no. 6246)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04421nam a22005055i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-0716-1960-5 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083643.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220221s2022 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781071619605 |
| -- | 978-1-0716-1960-5 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-0716-1960-5 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RA1190-1270 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MMGT |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED106000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MKGT |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.90072 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | In Silico Methods for Predicting Drug Toxicity |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Emilio Benfenati. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 2nd ed. 2022. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer US : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2022. |
| 300 ## - online resource | |
| Extent | XIV, 680 p. 244 illus., 215 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 2425 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | QSAR Methods -- PBPK Modeling to Simulate the Fate of Compounds in Living Organisms -- Pharmacokinetic Tools and Applications -- In Silico Tools and Software to Predict ADMET of New Drug Candidates -- Development of In Silico Methods for Toxicity Prediction in Collaboration between Academia and the Pharmaceutical Industry -- Emerging Bioinformatics Methods and Resources in Drug Toxicology -- In Silico Prediction of Chemically-Induced Mutagenicity: A Weight of Evidence Approach Integrating Information from QSAR Models and Read-Across Predictions -- In Silico Methods for Chromosome Damage -- In Silico Methods for Carcinogenicity Assessment -- In Silico Models for Developmental Toxicity -- In Silico Models for Repeated-Dose Toxicity (RDT): Prediction of the No Observed Adverse Effect Level (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL) for Drugs -- In Silico Models for Predicting Acute Systemic Toxicity -- In Silico Models for Skin Sensitization and Irritation -- In Silico Models for Hepatotoxicity -- Machine Learning Models for Predicting Liver Toxicity -- Implementation of In Silico Toxicology Protocols in Leadscope -- Use of Lhasa Limited Products for the In Silico Prediction of Drug Toxicity -- Using VEGAHUB within a Weight-of-Evidence Strategy -- MultiCASE Platform for In Silico Toxicology -- Adverse Outcome Pathways as Versatile Tools in Liver Toxicity Testing -- The Use of In Silico Methods for the Regulatory Toxicological Assessment of Pharmaceutical Impurities -- Computational Modeling of Mixture Toxicity -- In Silico Methods for Ecological Risk Assessment: Principles, Tiered Approaches, Applications, and Future Perspectives -- Increasing the Value of Data within a Large Pharmaceutical Company through In Silico Models. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This fully updated book explores all-new and revised protocols involving the use of in silico models, particularly with regard to pharmaceuticals. Divided into five sections, the volume covers the modeling of pharmaceuticals in the body, toxicity data for modeling purposes, in silico models for multiple endpoints, a number of platforms for evaluating pharmaceuticals, as well as an exploration of challenges, both scientific and sociological. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and implementation advice necessary for successful results. Authoritative and comprehensive, In Silico Methods for Predicting Drug Toxicity, Second Edition aims to guide the reader through the correct procedures needed to harness in silico models, a field which now touches a wide variety of research specialties. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Computer simulation. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Computer Modelling. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Benfenati, Emilio. |
| Relator term | editor. |
| Authority record control number or standard number | (orcid)0000-0002-3976-5989 |
| Real World Object URI | https://orcid.org/0000-0002-3976-5989 |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071619599 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071619612 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071619629 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 2425 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-0716-1960-5">https://doi.org/10.1007/978-1-0716-1960-5</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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