Experimental Cholestasis Research (Record no. 5706)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04816nam a22004815i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-4939-9420-5 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083633.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190423s2019 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781493994205 |
| -- | 978-1-4939-9420-5 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4939-9420-5 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM300-666 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MMG |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED071000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MKG |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Experimental Cholestasis Research |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Mathieu Vinken. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2019. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer New York : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2019. |
| 300 ## - online resource | |
| Extent | XIII, 399 p. 74 illus., 60 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 1981 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Mechanisms of Drug-Induced Cholestasis -- LC-MS/MS Analysis of Bile Acids in In Vitro Samples -- Pipe-3D: A Pipeline Based on Immunofluorescence, 3D Confocal Imaging, Reconstructions, and Morphometry for Biliary Network Analysis in Cholestasis -- Vesicle-Based and Hepatocyte-Based Assays for Identification of Drug Candidates Inhibiting BSEP Function -- The C-DILI™ Assay: An Integrated In Vitro Approach to Predict Cholestatic Hepatotoxicity -- In Vivo Measurement of Hepatic Drug Transporter Inhibition with Radiolabeled Bile Acids -- Measuring the Impact of Bile Acids on the Membrane Order of Primary Hepatocytes and Isolated Mitochondria by Fluorescence Imaging and Spectroscopy -- The Role and Study of Mitochondrial Impairment and Oxidative Stress in Cholestasis -- Measuring Apoptosis and Necrosis in Cholestatic Liver Injury -- Necrosome Formation and Necroptosis in Experimental Cholestasis -- Proteomics in Primary Biliary Cholangitis -- Transcriptomics Analysis of Cholestatic Compounds In Vitro -- Systems Microscopy of Stress Response Pathways in Cholestasis Research -- Mouse Models for Diseases in the Cholangiocyte Lineage -- Common Bile Duct Ligation as Model for Secondary Biliary Cirrhosis -- 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine Diet: A Rodent Model in Cholestasis Research -- A Rotavirus-Induced Mouse Model to Study Biliary Atresia and Neonatal Cholestasis -- Zebrafish as a Model to Study Cholestatic Liver Diseases -- Set-Up and Use of HepaRG Cells in Cholestasis Research -- Organotypic 3D HepaRG Liver Model for Assessment of Drug-Induced Cholestasis -- Establishment of Sandwich Cultures of Primary Human Hepatocytes -- Detection of Drug-Induced Cholestasis Potential in Sandwich-Cultured Human Hepatocytes -- Ex Vivo Model in Cholestasis Research -- Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies -- Use of Biliary Organoids in Cholestasis Research -- In Silico Approaches to Predict Drug-Transporter Interaction Profiles: Data Mining, Model Generation, and Link to Cholestasis. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This detailed book provides a state-of-the-art compilation of protocols relevant for the experimental study of cholestasis, each written by internationally recognized research teams that have built up long-standing expertise regarding one or more aspects of experimental cholestasis research. The first half of the collection examines methods targeted towards studying established and new mechanisms of cholestasis, while the second half explores experimental models and tools to investigate mechanisms of cholestasis and/or to predict cholestatic properties of drugs. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Experimental Cholestasis Research serves as an ideal guide for basic andapplied researchers pursuing this vital area of research in pharmacology and toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Internal medicine. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Internal Medicine. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vinken, Mathieu. |
| Relator term | editor. |
| Authority record control number or standard number | (orcid)0000-0001-5115-8893 |
| Real World Object URI | https://orcid.org/0000-0001-5115-8893 |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493994199 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493994212 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493994229 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 1981 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-4939-9420-5">https://doi.org/10.1007/978-1-4939-9420-5</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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