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Translational Research Methods in Neurodevelopmental Disorders (Record no. 5660)

MARC details
000 -LEADER
fixed length control field 04298nam a22005055i 4500
001 - CONTROL NUMBER
control field 978-1-0716-2569-9
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260610083633.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220929s2022 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781071625699
-- 978-1-0716-2569-9
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-0716-2569-9
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC321-580
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSAN
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI089000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSAN
Source thema
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 612.8
Edition information 23
245 10 - TITLE STATEMENT
Title Translational Research Methods in Neurodevelopmental Disorders
Medium [electronic resource] /
Statement of responsibility, etc. edited by Stéphane Martin, Frédéric Laumonnier.
250 ## - EDITION STATEMENT
Edition statement 1st ed. 2022.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture New York, NY :
Name of producer, publisher, distributor, manufacturer Springer US :
-- Imprint: Humana,
Date of production, publication, distribution, manufacture, or copyright notice 2022.
300 ## - online resource
Extent XIII, 264 p. 50 illus., 44 illus. in color.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
490 1# - SERIES STATEMENT
Series statement Neuromethods,
International Standard Serial Number 1940-6045 ;
Volume/sequential designation 185
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Using Lentiviral shRNA Delivery to Knock-Down Proteins in Cultured Neurons and In Vivo -- Synaptosomal Preparation and Its Application in Preclinical Studies -- Assessing the Nanoscale Organization of Excitatory and Inhibitory Synapses using Recombinant Probes to Visualize Endogenous Synaptic Proteins -- Agonist-Induced Functional Analysis and Cell Sorting (aiFACS) to Select and Characterize Interneurons during Brain Development -- A CRISPR/Cas9-Based Toolkit to Test Gain- and Loss-of-Gene Function in Brain Organoids -- Assessment of Adult Mouse Brain NeuroAnatomical Phenotypes using Quantitative and Precision Histology -- Leveraging Microelectrode Array Technology for Phenotyping Stem Cell-Derived Neurodevelopmental Disease Models -- Humanized Chimeric Mouse Models to Study Human Neural Development and Pathogenesis of Brain Diseases -- In Vivo Manipulations to Correct for Behavioral Phenotypes in Cognitive Disorder Mouse Models -- Assessing Dyadic Social Interactions in Rodent Models of Neurodevelopmental Disorders -- Central and Peripheral Explorations by Metabolomics to Study Neurodevelopmental Disorders -- Genetic Engineering of Non-Human Primates Models for Studying Neurodevelopmental Disorders.
520 ## - SUMMARY, ETC.
Summary, etc. This volume explores the latest techniques used to study neurodevelopmental diseases (NDD) that range from molecular aspects to integrated research approaches and brain imaging in living rodents. Chapters in this book cover topics such as protocols to deliver shRNA in vitro and in vivo using lentiviral particles to knock-down specific protein expression; experimental procedures to use recombinant fluorescent probes to visualize endogenous proteins at the mammalian synapse; CRISPR/Cas9 toolkit to assess either gain- or loss-of-gene function in brain organoids; detailed protocols to use in vivo manipulations to correct the behavioral phenotypes in cognitive disorder mouse lines; and experimental approaches to genetically engineer macaque models of NDDs and investigate how genetic predisposition may cause neural and functional alterations. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Research Methods in Neurodevelopmental Disorders is a valuable resource for all researchers who want to learn more about this important and developing field. .
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neurosciences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Medicine
General subdivision Research.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biology
General subdivision Research.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neuroscience.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Translational Research.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Martin, Stéphane.
Relator term editor.
Authority record control number or standard number (orcid)0000-0001-6771-7645
Real World Object URI https://orcid.org/0000-0001-6771-7645
Relationship edt
-- http://id.loc.gov/vocabulary/relators/edt
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Laumonnier, Frédéric.
Relator term editor.
Relationship edt
-- http://id.loc.gov/vocabulary/relators/edt
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer Nature eBook
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781071625682
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781071625705
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781071625712
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Neuromethods,
International Standard Serial Number 1940-6045 ;
Volume/sequential designation 185
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1007/978-1-0716-2569-9">https://doi.org/10.1007/978-1-0716-2569-9</a>
912 ## -
-- ZDB-2-PRO

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