High-Throughput Screening Assays in Toxicology (Record no. 5639)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04127nam a22004935i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-0716-2213-1 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083632.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220316s2022 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781071622131 |
| -- | 978-1-0716-2213-1 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-0716-2213-1 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RA1190-1270 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MMGT |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED106000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MKGT |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.90072 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | High-Throughput Screening Assays in Toxicology |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Hao Zhu, Menghang Xia. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 2nd ed. 2022. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer US : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2022. |
| 300 ## - online resource | |
| Extent | XII, 200 p. 54 illus., 32 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 2474 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Cell-Based Assays to Identify ERR and ERR/PGC Modulators -- Mitochondrial Membrane Potential Assay -- Cell-Based hERG Inhibition Assay in a High-Throughput Format -- Identifying CAR Modulators Utilizing a Reporter Gene Assay -- Study Liver Cytochrome P450 3A4 Inhibition and Hepatotoxicity Using DMSO-Differentiated HuH-7 Cells -- Acetylcholinesterase Inhibition Assays for High-Throughput Screening -- Cell-Based Assays to Identify Modulators of Nrf2/ARE Pathway -- Cell-Based Imaging Assay for Detection of Phospholipdosis -- GFP-LC3 High-Content Assay for Screening Autophagy Modulators -- Generation of iPSC-Derived Brain Organoids for Drug Testing and Toxicological Evaluation -- Zebrafish Behavioral Assays in Toxicology -- High Throughput Screening Assay Profiling for Large Chemical Databases -- A Quantitative High Throughput Screening Data Analysis Pipeline for Activity Profiling -- CurveP Method for Rendering High Throughput Screening Dose-Response Data into Digital Fingerprints -- Accounting for Artifacts in High Throughput Toxicity Assays -- Automatic Quantitative Structure-Activity Relationship Modeling to Fill Data Gaps in High-Throughput Screening -- Use In Silico and In Vitro Methods to Screen Hepatotoxic Chemicals and CYP450 Enzyme Inhibitors. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This second edition volume expands on the previous edition by exploring the latest advancements in high throughput screening (HTS) in toxicity studies by using in vitro, ex vivo, and in vivo models. This volume also covers the application of artificial intelligence (AI) and data science to curate, manage, and use HTS data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, High Throughput Screening Assays in Modern Toxicology, Second Edition is a valuable resource for scientists pursuing chemical toxicology research. This book will aid scientists and researchers in translating new HTS techniques into standardized chemical toxicology assessment tools that can refine, reduce, and replace animal testing. . |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biological assay. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Assay Systems. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhu, Hao. |
| Relator term | editor. |
| Authority record control number or standard number | (orcid)0000-0002-3559-6129 |
| Real World Object URI | https://orcid.org/0000-0002-3559-6129 |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xia, Menghang. |
| Relator term | editor. |
| Authority record control number or standard number | (orcid)0000-0001-7285-8469 |
| Real World Object URI | https://orcid.org/0000-0001-7285-8469 |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071622124 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071622148 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781071622155 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Biology, |
| International Standard Serial Number | 1940-6029 ; |
| Volume/sequential designation | 2474 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-0716-2213-1">https://doi.org/10.1007/978-1-0716-2213-1</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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