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Computer-Aided Antibody Design (Record no. 5458)

MARC details
000 -LEADER
fixed length control field 06336nam a22006495i 4500
001 - CONTROL NUMBER
control field 978-1-0716-2609-2
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260610083629.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 221108s2023 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781071626092
-- 978-1-0716-2609-2
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-0716-2609-2
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QR180-189.5
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJCM
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED044000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJCM
Source thema
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 571.96
Edition information 23
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.079
Edition information 23
245 10 - TITLE STATEMENT
Title Computer-Aided Antibody Design
Medium [electronic resource] /
Statement of responsibility, etc. edited by Kouhei Tsumoto, Daisuke Kuroda.
250 ## - EDITION STATEMENT
Edition statement 1st ed. 2023.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture New York, NY :
Name of producer, publisher, distributor, manufacturer Springer US :
-- Imprint: Humana,
Date of production, publication, distribution, manufacture, or copyright notice 2023.
300 ## - online resource
Extent XIV, 491 p. 139 illus., 118 illus. in color.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
341 0# - ACCESSIBILITY CONTENT
Textual assistive features Table of contents navigation
Source onix
341 0# - ACCESSIBILITY CONTENT
Textual assistive features Single logical reading order
Source onix
341 0# - ACCESSIBILITY CONTENT
Textual assistive features Short alternative textual descriptions
Source onix
341 0# - ACCESSIBILITY CONTENT
Textual assistive features Use of color is not sole means of conveying information
Source onix
341 0# - ACCESSIBILITY CONTENT
Textual assistive features Use of high contrast between text and background color
Source onix
341 0# - ACCESSIBILITY CONTENT
Textual assistive features Next / Previous structural navigation
Source onix
341 0# - ACCESSIBILITY CONTENT
Textual assistive features All non-decorative content supports reading without sight
Source onix
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
490 1# - SERIES STATEMENT
Series statement Methods in Molecular Biology,
International Standard Serial Number 1940-6029 ;
Volume/sequential designation 2552
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Antibody sequence and structure analyses using IMGT®: 30 years of immunoinformatics -- Structural Classification of CDR-H3 in Single-Domain VHH Antibodies -- Computational modelling of Antibody and T Cell receptor (CDR3 loops) -- Molecular dynamics simulation for investigating antigen-antibody interaction -- Molecular Dynamics Methods for Antibody Design -- Probing antibody dynamics with geometric simulations -- PITHA: a webtool to predict immunogenicity for humanized and fully human therapeutic antibodies -- Thermal Stability Estimation of Single Domain Antibodies Using Molecular Dynamics Simulations -- Assessing and engineering antibody stability using experimental and computational methods -- In Silico Prediction Method for Protein Asparagine Deamidation -- Structure-based Optimization of Antibody-Based Biotherapeutics for Improved Developability: A Practical Guide for Molecular Modelers -- B-cell epitope predictions using computational methods -- Computational Epitope Prediction and Design for Antibody Development and Detection -- Information-driven antibody-antigen modelling with HADDOCK -- Structural modeling of adaptive immune responses to infection -- Protein-Protein Interaction Modelling with the Fragment Molecular Orbital Method -- Structural Considerations in Affinity Maturation of Antibody-Based Biotherapeutic Candidates -- Structure-based affinity maturation of antibody based on double-point mutations -- Antibody affinity maturation using computational methods: from an initial hit to small scale expression of optimised binders -- Optimizing Antibody-Antigen Binding Affinities with the ADAPT Platform -- Using graph-based signatures to guide rational antibody engineering -- A computational framework for determining the breadth of antibodies against highly mutable pathogens -- Analytical method for experimental validation of computer-designed antibody -- Computational analysis of antibody paratopes for antibody sequences in antibody libraries -- Bioinformatic Analysis of Natively Paired VH:VL Antibody Repertoires for Antibody Discovery -- Analyzing antibody repertoire using next-generation sequencing and machine learning -- A computational pipeline for predicting cancer neoepitopes. .
520 ## - SUMMARY, ETC.
Summary, etc. This volume details state-of-the- art methods on computer-aided antibody design. Chapters guide readers through information on antibody sequences and structures, modeling antibody structures and dynamics, prediction and optimization of biological and biophysical properties of antibodies, prediction of antibody-antigen interactions, and computer-aided antibody affinity maturation and beyond. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Computer-Aided Antibody Design aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. Chapter 2 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
532 8# - ACCESSIBILITY NOTE
Summary of accessibility Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com.
532 8# - ACCESSIBILITY NOTE
Summary of accessibility No reading system accessibility options actively disabled
532 8# - ACCESSIBILITY NOTE
Summary of accessibility Publisher contact for further accessibility information: accessibilitysupport@springernature.com
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Immunology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Bioinformatics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pharmaceutical chemistry.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Immunology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Bioinformatics.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pharmaceutics.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Tsumoto, Kouhei.
Relator term editor.
Authority record control number or standard number (orcid)0000-0001-7643-5164
Real World Object URI https://orcid.org/0000-0001-7643-5164
Relationship edt
-- http://id.loc.gov/vocabulary/relators/edt
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kuroda, Daisuke.
Relator term editor.
Relationship edt
-- http://id.loc.gov/vocabulary/relators/edt
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer Nature eBook
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781071626085
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781071626108
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781071626115
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Methods in Molecular Biology,
International Standard Serial Number 1940-6029 ;
Volume/sequential designation 2552
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1007/978-1-0716-2609-2">https://doi.org/10.1007/978-1-0716-2609-2</a>
912 ## -
-- ZDB-2-PRO

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