Synaptosomes (Record no. 5193)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04051nam a22004575i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-4939-8739-9 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260610083624.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180921s2018 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781493987399 |
| -- | 978-1-4939-8739-9 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4939-8739-9 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC321-580 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSAN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI089000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSAN |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 612.8 |
| Edition information | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Synaptosomes |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Kathryn M. Murphy. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2018. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer New York : |
| -- | Imprint: Humana, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2018. |
| 300 ## - online resource | |
| Extent | XV, 312 p. 55 illus., 32 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Neuromethods, |
| International Standard Serial Number | 1940-6045 ; |
| Volume/sequential designation | 141 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Introduction to Synaptosome Methods and Applications -- Victor P. Whittaker: The Discovery of the Synaptosome and Its Implications -- Synaptosome Preparations: Which Procedure Should I Use? -- Protocol for a High-Throughput Semi-Automated Preparation for Filtered Synaptoneurosomes -- Subcellular Fractionation of Brain Tissue from Small Tissue Explants -- Preparation of P2 of Percoll-Purified Synaptosomes from Mammalian Brain Tissue -- Synaptosomal Bioenergetics and Glutamate Release -- Synaptosomes Bioenergetics and Calcium Handling: Aging Response -- Isolation of Highly Purified and Functionally Active Synaptic Mitochondria -- Affinity Proteomics for Interactome and Phosphoproteome Screening in Synaptosomes -- Manipulating Synapse-Enriched Biochemical Fractions to Detect a Purified Synaptic Protein’s Effect on Neurotransmitter Release -- Prosomes: Supramolecular Structures at the Synaptosome Membrane Involved in Vesicle Docking, Fusion,and Neurotransmitter Release -- SMPL-Synaptic Membranes: Nanodisc-Mediated Synaptic Membrane Mimetics Expand the Toolkit for Drug Discovery and the Molecular Cell Biology of Synapses -- Profiling of MicroRNA and Protein from Purified Synaptoneurosomes in a Neurodegenerative Disease Model -- Use of Synaptoneurosome Samples to Study Development and Plasticity of Human Cortex -- The Use of Synaptosomes in Studying Autism Spectrum Disorder and Other Neurodevelopmental Disorders -- Flow Cytometric Evaluation of Crude Synaptosome Preparation as a Way to Study Synaptic Alteration in Neurodegenerative Diseases. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This volume describes techniques to make synaptosomes, and discusses numerous ways that synaptosomes are used to study and answer diverse questions about synapses. After examining the history that led to making synaptosomes, the chapters delved into its important as a tool to explore synaptic connections. Some of the topics covered in this book are: synaptosome bioenergetics and glutamate release; affinity proteomics for interactome and phosphoproteome screening in synaptosomes; isolation of highly purified and functionally active synaptic mitochondria; and profiling of microRNA and protein from purified synaptoneurosomes in a neurodegenerative disease model. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Synaptosomes is a valuable resource for any researcher interested in learning more about this developing field. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neurosciences. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neuroscience. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Murphy, Kathryn M. |
| Relator term | editor. |
| Relationship | edt |
| -- | http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493987382 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493987405 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781493993796 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Neuromethods, |
| International Standard Serial Number | 1940-6045 ; |
| Volume/sequential designation | 141 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-1-4939-8739-9">https://doi.org/10.1007/978-1-4939-8739-9</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
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