Mobile DNA is an online, peer-reviewed, open access journal that publishes articles providing novel insights into the function, biological impact, and evolution of transposable elements in any organism. Topics related to transposable elements may include genetic or epigenetic variation, genome rearrangements, mechanisms, patterns and processes of transposition, and the role of mobile elements in host genome evolution. Mobile DNA aims to understand: mechanisms of intra- and intergenomic mobility via genetic, comparative genomic, biochemical and structural approaches regulation of DNA rearrangements by the environment and during development how DNA restructuring reshapes cellular function and organism evolution the role of transposable elements in disease in a variety of organisms host—element interaction and genetic/epigenetic regulatory networks Mobile DNA reflects the need for a journal that spans all aspects of specialized recombination, from structure and mechanism to evolutionary impact. In addition, the journal will consider articles on the utility of mobile genetic elements in biotechnological methods and protocols, and related biocomputational tools.